ISSN:
1420-9071
Keywords:
RecA
;
RecA-DNA complexes
;
homologous recombination
;
Rad51 protein
;
electron microscopy
;
image analysis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract While theE. coli RecA protein has been the most intensively studied enzyme of homologous recombination, the unusual RecA-DNA filament has stood alone until very recently. It now appears that this protein is part of a universal family that spans all of biology, and the filament that is formed by the protein on DNA is a universal structure. With RecA's role in recombination given new and greatly increased significance, we focus in this review on the energetics of the RecA-mediated strand exchange and the relation between the energetics and recombination spanning heterologous inserts.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01924002
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