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  • 1
    Electronic Resource
    Electronic Resource
    Milling of paddy in relation to yield and quality of rice of different Indian varieties (1975)
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 23 (1975), S. 1183-1185 
    Details
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jf60202a035
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  • 2
    Electronic Resource
    Electronic Resource
    Single-dose pharmacokinetics of citalopram in patients with moderate renal insufficiency or hepatic cirrhosis compared with healthy subjects (1998)
    Springer
    European journal of clinical pharmacology 54 (1998), S. 237-242 
    Details
    ISSN: 1432-1041
    Keywords: Key words Cirrhosis ; Citalopram ; Renal impairment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objective: To compare the pharmacokinetics of the antidepressant citalopram and its metabolites demethylcitalopram and didemethylcitalopram in subjects with moderate renal insufficiency and subjects with hepatic cirrhosis with that in healthy subjects. Methods: Pharmacokinetic parameters from three individual, open-label, phase I trials were derived following single oral or intravenous citalopram dose (40 mg) to healthy subjects and a single oral dose (20 mg) to patients. Serum and urine concentrations of citalopram and metabolites were determined using a validated HPLC method. Results: The absolute bioavailability of citalopram tablets in healthy subjects was 80%. The renal clearance was a minor component (〈20%) of the total elimination of citalopram. Serum Cmax and t max for citalopram were essentially unaffected by the occurrence of renal or hepatic disease. In comparison with healthy subjects, renal impairment was associated with a significant reduction in the renal elimination of citalopram and its two metabolites and a slight prolongation of serum citalopram t 1/2 (49.5 h vs 36.8 h in healthy subjects).␣Cirrhosis resulted in significant decrease in citalopram CLoral␣(0.21 vs 0.33 l · h−1· kg−1 in healthy subjects) and increase in Vz· f −1, with an approximately twofold increase in t 1/2 (83.4 h vs 36.8 h in healthy subjects). Indices of renal (creatinine or 51Cr-EDTA clearances) and hepatic (galactose elimination capacity or Child-Pugh score) function were poor predictors of the changes in the pharmacokinetics of citalopram and its metabolites in these populations. Conclusion: No reduction of citalopram dosage is warranted in patients with moderately impaired renal function. However, that may not apply for patients with severe renal failure. In patients with impaired hepatic function, prescription of a lower dosage of citalopram may be appropriate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002280050452
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  • 3
    Electronic Resource
    Electronic Resource
    Assessment of bioelectrical impedance for individualising gentamicin therapy in neonates (1993)
    Springer
    European journal of clinical pharmacology 44 (1993), S. 253-258 
    Details
    ISSN: 1432-1041
    Keywords: Bioelectrical impedance ; Gentamicin ; non-invasive technique ; neonates ; predictive models ; pharmacokinetics ; plasma levels
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The use of bioelectrical impedance (BI) analysis as a non-invasive approach for individualising gentamicin therapy in newborn infants has been investigated in a two phase study. In Phase I, 1/impedance and length2 were identified as statistically significant predictors of the distribution volume of gentamicin (Adj R2=0.78, CV=12.42%), and length2/impedance and post-conceptual age were predictors of total systemic clearance (Adj R2=0.83, CV=14.5%), following the administration of 2.5 mg·kg−1 gentamicin to 17 neonates (gestational age (GA) 27 to 36 weeks). In a prospective validation of these relationships in an independent (Phase II) group of 27 infants (GA 26 to 41 weeks), predicted serum gentamicin concentrations were close to those achieved. Several instances of high prediction errors (predicted minus achieved levels) were observed in infants with known or suspected renal impairment and they caused significant (P〈0.05) perturbation in the bias and accuracy of the models. Daily BI measures over a four to five day period were able to detect individual changes in the fat-free body compartments, which were translated into alterations in gentamicin regimens. This simple, non-invasive and relatively inexpensive bedside technique provides a potentially valuable means to individualise gentamicin therapy without relying on the measurement of serum gentamicin concentration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00271367
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  • 4
    Electronic Resource
    Electronic Resource
    Determination of the angular and energy dependence of hard constituent scattering from π^0 pair events at the CERN intersecting storage rings
    Amsterdam : Elsevier
    Nuclear Physics, Section B 209 (1982), S. 284-300 
    Details
    ISSN: 0550-3213
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0550-3213(82)90256-5
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  • 5
    Electronic Resource
    Electronic Resource
    Excimer laser projection micromachined free-standing polymer films
    Amsterdam : Elsevier
    Optics and Lasers in Engineering 6 (1985), S. 67-77 
    Details
    ISSN: 0143-8166
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Electrical Engineering, Measurement and Control Technology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics , Technology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0143-8166(85)90015-6
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  • 6
    Electronic Resource
    Electronic Resource
    Spectroscopic and fast photographic studies of excimer laser polymer ablation (1988)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 64 (1988), S. 4657-4663 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Spectroscopy and fast photography have been used to study the luminous plume produced by ablative etching of polyimide and polyethylene-terephthalate polymer films with the XeCl laser. The time dependence of the expansion for various environmental gas pressures has been studied in this way. The results show that at low pressures (〈0.5 mb) the expansion approaches a free expansion into a vacuum, while at 15 mb the time dependence is close to that predicted by an ideal blast wave model. It is suggested that a significant fraction of the luminous species detected spectroscopically may be created in the shock front at the plume/environmental gas interface.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.341247
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  • 7
    Electronic Resource
    Electronic Resource
    Screening of wild Oryza species against bacterial leaf blight (Xanthomonas oryzae py. oryza) pathotypes of Punjab (India) (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Plant breeding 117 (1998), S. 0 
    Details
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: One-hundred and sixty-seven accessions belonging to 13 wild Oryza species were screened against the bacterial leaf blight (BB) pathogen (Xanthomonas oryzae pv. oryza) in Punjab, India. Nine species were identified as carrying resistant genes against the four most prevalent pathotypes under conditions in Punjab. These included O. barthii (eight accessions), O. longistaminata (five accessions), O. meridionalis (three accessions), O. nivara (five accessions), O. rufipogen (two accessions), and one accession each from O. punctata, O. minuta, O. malampuzhaensis and O. latifolia. This is the first report showing the availability of BB resistance in two species namely, O. meridionalis and O. punctata. The resistant accessions, especially those with a similar genome (AA) could potentially be used for the transfer of BB resistance to well-adapted high-yielding rice cultivars.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0523.1998.tb01980.x
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  • 8
    Electronic Resource
    Electronic Resource
    Excimer laser ablation and thermal coupling efficiency to polymer films (1985)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 57 (1985), S. 1420-1422 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Thermal coupling and etch rate measurements are reported for polyethylene terephthalate and polyimide films irradiated at excimer laser wavelengths of 193, 248, and 308 nm. Thermal energy balance is observed up to a threshold fluence but above this the energy absorbed remains approximately constant, the excess energy being carried away by the ablated material. The ablated material appears to have a temperature 〉103 K as determined by calculations based on the thermal energy loading and relaxation time estimated from IR measurements. These results provided useful information on the interaction mechanism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.334503
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  • 9
    Electronic Resource
    Electronic Resource
    Novel method for measuring excimer laser ablation thresholds of polymers (1988)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 52 (1988), S. 1880-1882 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Conical features produced on excimer laser ablated polymers are shown to provide a sensitive technique for determining ablation thresholds. This has been applied to polyimide, polyethylene terephthalate, polyethylene, and nylon 66 ablated using the 157 nm vacuum ultraviolet F2 laser.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.99612
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  • 10
    Electronic Resource
    Electronic Resource
    Peroxidase Isozyme Pattern in Pearl Millet Lines Resistant and Susceptible to Downy Mildew (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Plant breeding 101 (1988), S. 0 
    Details
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Peroxidase isozyme patterns of five downy mildew (DM) resistant inbred lines (PIB-57-1, PIB-1248, PIB-1356, PIB-1364 and PIB-1440), five susceptible lines (PIB-1335-1-1, PIB-1314-2-2, PIB-2231-1, 7042 and PIB-1530-1-1) and DM free plants from the susceptible lines of pearl millet were studied. The results suggested a possible involvement of an isoperoxidase (C9) in imparting the resistance. The involvement of two other isozymes (C5 and C6) was also indicated in the1 resistance mechanism. The specific differentiation m particular isozyme pattern can be a useful criterion for characterization of resistance to downy mildew.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0523.1988.tb00296.x
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