ISSN:
0268-2605
Keywords:
Asymmetric hydrosilylation
;
bis(N-benzyl-N-methylephedrinium) hexachloroplatinate(IV)
;
N-benzyl-N-methylephedrinium bromotrichlororhodate(III)
;
( - )-bis(N-benzyl-N-methylephedrinium) dibromodichlorozincate(II)
;
chiral synthesis, enantioselectivity
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
N-benzyl-N-methylephedrinium hexachloroplatinate(IV), bromotrichlororhodate(III), and dibromodichlorozincate(II) have been synthesized by reacting ( - )-N-benzyl-N-methylephedrinium bromide with K2PtCl6, RhCl3 · 4H2O and ZnCl2, respectively. The above halometallates have been found to catalyse the asymmetric hydrosilylation of acetophenone and 3-acetylpyridine with diphenylsilane. The hydrosilylation of 3-acetylpyridine in the presence of ( - )-N-benzyl-N-methylephedrinium zincate followed by silyl ether hydrolysis gives 1-(3-pyridyl)ethanol in ca 50% optical yield.
Additional Material:
1 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/aoc.590010508
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