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  • 1
    Publication Date: 2015-05-29
    Description: Nature Geoscience 8, 479 (2015). doi:10.1038/ngeo2437 Authors: J. M. Whittaker, J. C. Afonso, S. Masterton, R. D. Müller, P. Wessel, S. E. Williams & M. Seton Plate tectonic motions are commonly considered to be driven by slab pull at subduction zones and ridge push at mid-ocean ridges, with motion punctuated by plumes of hot material rising from the lower mantle. Within this model, the geometry and location of mid-ocean ridges are considered to be independent of lower-mantle dynamics, such as deeply sourced plumes that produce voluminous lava eruptions—termed large igneous provinces. Here we use a global plate model to reconstruct the locations of large igneous provinces relative to plumes and mid-ocean ridges at the time they formed. We find that large igneous provinces repeatedly formed at specific locations where mid-ocean ridges and plumes interact. We calculate how much mantle material was converted to oceanic lithosphere at the mid-ocean ridges and find that slowly migrating ridge systems that have been stabilized by upwelling plumes have extracted large volumes of material from the same part of the upper mantle over periods up to 180 million years. The geochemical signatures of mid-ocean ridge basalts and seismic tomographic data show that upper-mantle temperatures are elevated at significant distances from ridge–plume interactions, indicating a far-field, indirect influence of plume–ridge interactions on the upper-mantle structure. We conclude that strong feedbacks exist between the dynamics of slowly migrating ridges and deeply sourced plumes.
    Print ISSN: 1752-0894
    Electronic ISSN: 1752-0908
    Topics: Geosciences
    Published by Springer Nature
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  • 2
    Publication Date: 2015-08-01
    Description: Earth's mightiest ocean current, the Antarctic Circumpolar Current (ACC), regulates the exchange of heat and carbon between the ocean and the atmosphere, and influences vertical ocean structure, deep-water production and the global distribution of nutrients and chemical tracers. The eastward-flowing ACC occupies a unique circumglobal pathway in the Southern Ocean that was enabled by the tectonic opening of key oceanic gateways during the break-up of Gondwana (for example, by the opening of the Tasmanian Gateway, which connects the Indian and Pacific oceans). Although the ACC is a key component of Earth's present and past climate system, the timing of the appearance of diagnostic features of the ACC (for example, low zonal gradients in water-mass tracer fields) is poorly known and represents a fundamental gap in our understanding of Earth history. Here we show, using geophysically determined positions of continent-ocean boundaries, that the deep Tasmanian Gateway opened 33.5 +/- 1.5 million years ago (the errors indicate uncertainty in the boundary positions). Following this opening, sediments from Indian and Pacific cores recorded Pacific-type neodymium isotope ratios, revealing deep westward flow equivalent to the present-day Antarctic Slope Current. We observe onset of the ACC at around 30 million years ago, when Southern Ocean neodymium isotopes record a permanent shift to modern Indian-Atlantic ratios. Our reconstructions of ocean circulation show that massive reorganization and homogenization of Southern Ocean water masses coincided with migration of the northern margin of the Tasmanian Gateway into the mid-latitude westerly wind band, which we reconstruct at 64 degrees S, near to the northern margin. Onset of the ACC about 30 million years ago coincided with major changes in global ocean circulation and probably contributed to the lower atmospheric carbon dioxide levels that appear after this time.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Scher, Howie D -- Whittaker, Joanne M -- Williams, Simon E -- Latimer, Jennifer C -- Kordesch, Wendy E C -- Delaney, Margaret L -- England -- Nature. 2015 Jul 30;523(7562):580-3. doi: 10.1038/nature14598.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Earth and Ocean Sciences, University of South Carolina, Columbia, South Carolina 29208, USA. ; Institute for Marine and Antarctic Studies, University of Tasmania, Hobart, Tasmania 7001, Australia. ; EarthByte group, School of Geosciences, The University of Sydney, Sydney, New South Wales 2006, Australia. ; Department of Earth and Environmental Systems, Indiana State University, Terre Haute, Indiana 47809, USA. ; Department of Ocean and Earth Science, National Oceanography Centre, University of Southampton, Waterfront Campus, European Way, Southampton SO14 3ZH, UK. ; Ocean Sciences Department and Institute of Marine Sciences, University of California Santa Cruz, Santa Cruz, California 95064, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/26223626" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antarctic Regions ; Atmosphere/chemistry ; Carbon/analysis ; Carbon Dioxide/analysis ; Climate ; Fishes ; Fossils ; Geologic Sediments/chemistry ; History, Ancient ; Hot Temperature ; Isotopes ; Neodymium/analysis ; Oceans and Seas ; Seawater/analysis/chemistry ; Tooth ; *Water Movements ; *Wind
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 3
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1992-09-11
    Description: The carnivorous habit in flowering plants represents a grade of structural organization. Different morphological features associated with the attraction, trapping, and digestion of prey characterize a diversity of specialized forms, including the familiar pitcher and flypaper traps. Phylogenetic analysis of nucleotide sequence data from the plastic rbcL gene indicates that both carnivory and stereotyped trap forms have arisen independently in different lineages of angiosperms. Furthermore, these results demonstrate that flypaper traps share close common ancestry with all other trap forms. Recognition of these patterns of diversification may provide ideal, naturally occurring systems for studies of developmental processes underlying macromorphological evolution in angiosperms.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Albert, V A -- Williams, S E -- Chase, M W -- New York, N.Y. -- Science. 1992 Sep 11;257(5076):1491-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1523408" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; *Biological Evolution ; Molecular Sequence Data ; *Phylogeny ; *Plant Physiological Phenomena ; Plants/*classification/genetics ; Polymerase Chain Reaction ; Restriction Mapping
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 2004-11-06
    Description: Modulation of calcium-sensitive potassium (BK) channels by oxygen is important in several mammalian tissues, and in the carotid body it is crucial to respiratory control. However, the identity of the oxygen sensor remains unknown. We demonstrate that hemoxygenase-2 (HO-2) is part of the BK channel complex and enhances channel activity in normoxia. Knockdown of HO-2 expression reduced channel activity, and carbon monoxide, a product of HO-2 activity, rescued this loss of function. Inhibition of BK channels by hypoxia was dependent on HO-2 expression and was augmented by HO-2 stimulation. Furthermore, carotid body cells demonstrated HO-2-dependent hypoxic BK channel inhibition, which indicates that HO-2 is an oxygen sensor that controls channel activity during oxygen deprivation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Williams, Sandile E J -- Wootton, Phillippa -- Mason, Helen S -- Bould, Jonathan -- Iles, David E -- Riccardi, Daniela -- Peers, Chris -- Kemp, Paul J -- New York, N.Y. -- Science. 2004 Dec 17;306(5704):2093-7. Epub 2004 Nov 4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉School of Biomedical Sciences, University of Leeds, Leeds LS2 9JT, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15528406" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carbon Monoxide/*metabolism ; Carotid Body/*cytology/*physiology ; Cell Hypoxia ; Cell Line ; Heme/metabolism ; Heme Oxygenase (Decyclizing)/genetics/*metabolism ; Humans ; Immunoprecipitation ; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits ; Large-Conductance Calcium-Activated Potassium Channels ; Membrane Potentials ; NADP/metabolism ; Oxygen/*physiology ; Patch-Clamp Techniques ; Potassium Channels, Calcium-Activated ; RNA Interference ; RNA, Small Interfering/pharmacology ; Rats ; Transfection
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 2011-02-19
    Description: Stem and progenitor cells use asymmetric cell divisions to balance proliferation and differentiation. Evidence from invertebrates shows that this process is regulated by proteins asymmetrically distributed at the cell cortex during mitosis: Par3-Par6-aPKC, which confer polarity, and Galpha(i)-LGN/AGS3-NuMA-dynein/dynactin, which govern spindle positioning. Here we focus on developing mouse skin, where progenitor cells execute a switch from symmetric to predominantly asymmetric divisions concomitant with stratification. Using in vivo skin-specific lentiviral RNA interference, we investigate spindle orientation regulation and provide direct evidence that LGN (also called Gpsm2), NuMA and dynactin (Dctn1) are involved. In compromising asymmetric cell divisions, we uncover profound defects in stratification, differentiation and barrier formation, and implicate Notch signalling as an important effector. Our study demonstrates the efficacy of applying RNA interference in vivo to mammalian systems, and the ease of uncovering complex genetic interactions, here to gain insights into how changes in spindle orientation are coupled to establishing proper tissue architecture during skin development.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077085/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077085/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Williams, Scott E -- Beronja, Slobodan -- Pasolli, H Amalia -- Fuchs, Elaine -- R01 AR050452/AR/NIAMS NIH HHS/ -- R01 AR050452-07/AR/NIAMS NIH HHS/ -- R01AR27883/AR/NIAMS NIH HHS/ -- R37 AR027883/AR/NIAMS NIH HHS/ -- R37 AR027883-30/AR/NIAMS NIH HHS/ -- R37 AR027883-30S1/AR/NIAMS NIH HHS/ -- R37 AR027883-31/AR/NIAMS NIH HHS/ -- R37 AR027883-32/AR/NIAMS NIH HHS/ -- R37 AR027883-33/AR/NIAMS NIH HHS/ -- Howard Hughes Medical Institute/ -- England -- Nature. 2011 Feb 17;470(7334):353-8. doi: 10.1038/nature09793.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Howard Hughes Medical Institute, Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, New York 10065, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21331036" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carrier Proteins/genetics/metabolism ; *Cell Differentiation ; *Cell Division ; Cells, Cultured ; Epidermis/*cytology ; Female ; Gene Knockdown Techniques ; Keratinocytes/cytology ; Male ; Mice ; Microtubule-Associated Proteins/deficiency/genetics/metabolism ; Nuclear Proteins/deficiency/genetics/metabolism ; Receptors, Notch/genetics/*metabolism ; Signal Transduction ; Skin/cytology/embryology ; Spindle Apparatus/metabolism
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 6
    Publication Date: 1982-12-10
    Description: The rapid closure of leaves in the Venus flytrap (Dionaea muscipula) involves irreversible cell enlargement, which can be initiated by acidifying the cell walls to pH 4.50 and below. Leaves infiltrated with neutral buffers that keep the pH above 4.50 to 4.75 will not close in response to stimulation of their trigger hairs even though the action potentials that ordinarily cause closure are produced. During the 1 to 3 seconds required for closure about 29 percent of the cellular adenosine triphosphate is lost. It is likely that this adenosine triphosphate is used in very rapid transport of hydrogen ions from the motor cells and that the movement is due to a mechanism of "acid growth."〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Williams, S E -- Bennett, A B -- New York, N.Y. -- Science. 1982 Dec 10;218(4577):1120-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17752873" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
    Publication Date: 2016-05-14
    Description: Volcanic hotspot tracks featuring linear progressions in the age of volcanism are typical surface expressions of plate tectonic movement on top of narrow plumes of hot material within Earth's mantle. Seismic imaging reveals that these plumes can be of deep origin--probably rooted on thermochemical structures in the lower mantle. Although palaeomagnetic and radiometric age data suggest that mantle flow can advect plume conduits laterally, the flow dynamics underlying the formation of the sharp bend occurring only in the Hawaiian-Emperor hotspot track in the Pacific Ocean remains enigmatic. Here we present palaeogeographically constrained numerical models of thermochemical convection and demonstrate that flow in the deep lower mantle under the north Pacific was anomalously vigorous between 100 million years ago and 50 million years ago as a consequence of long-lasting subduction systems, unlike those in the south Pacific. These models show a sharp bend in the Hawaiian-Emperor hotspot track arising from the interplay of plume tilt and the lateral advection of plume sources. The different trajectories of the Hawaiian and Louisville hotspot tracks arise from asymmetric deformation of thermochemical structures under the Pacific between 100 million years ago and 50 million years ago. This asymmetric deformation waned just before the Hawaiian-Emperor bend developed, owing to flow in the deepest lower mantle associated with slab descent in the north and south Pacific.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hassan, Rakib -- Muller, R Dietmar -- Gurnis, Michael -- Williams, Simon E -- Flament, Nicolas -- England -- Nature. 2016 May 11;533(7602):239-42. doi: 10.1038/nature17422.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉EarthByte Group, School of Geosciences, University of Sydney, Sydney, New South Wales 2006, Australia. ; Seismological Laboratory, California Institute of Technology, Pasadena, California 91125, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/27172048" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 8
    Publication Date: 2013-06-26
    Description: Climate change is expected to significantly influence biodiversity, but the performance of climate change mitigation strategies in reducing these impacts is not yet known. Simulations of the future ranges of common and widespread species indicate that mitigation could reduce range loss by 60% if emissions peak in 2016, or by 40% if emissions peak in 2030. Nature Climate Change 3 678 doi: 10.1038/nclimate1887
    Print ISSN: 1758-678X
    Electronic ISSN: 1758-6798
    Topics: Geosciences
    Published by Springer Nature
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  • 9
    Publication Date: 2017-04-20
    Description: Northern Africa underwent widespread inundation during the Late Cretaceous. Changes in eustasy do not explain the absence of this inundation across the remainder of Africa and the timing and location of documented tectonic deformation does not explain the large-scale paleogeographic evolution. We investigate the combined effects of vertical surface displacements predicted by a series of mantle flow models and eustasy on northern African paleoenvironmental change. We compare changes in base level computed as the difference between eustasy and long-wavelength dynamic topography arising from sources of buoyancy deeper than 350 km to the evolution of paleoshorelines derived from two interpolated global datasets since the mid Cretaceous. We also compare the predicted mantle temperature field of these mantle flow models at present-day to several seismic tomography models. This approach reveals that dynamic subsidence, related to Africa's northward motion away from the buoyant regions overlying the African LLSVP, amplified sea-level rise, resulting in maximum inundation of northern Africa during the Cenomanian and Turonian. By the Cenozoic, decreased magnitudes of dynamic subsidence, reflecting the reduced draw-down effects of slab material beneath northern Africa associated with the impact of the Africa-Eurasia collision, combined with a comparatively pronounced progressive sea-level fall resulted in ongoing region-wide regression along coastal regions. The temporal match between our preferred model and the paleoshoreline datasets suggests that the paleogeographic evolution of this region since the Late Cretaceous has mainly been influenced by the interplay between eustasy and long-wavelength dynamic topography arising from large-scale, subduction-driven, lower mantle convection.
    Print ISSN: 0278-7407
    Electronic ISSN: 1944-9194
    Topics: Geosciences
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 112 (1990), S. 6711-6712 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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