ISSN:
1476-4687
Quelle:
Nature Archives 1869 - 2009
Thema:
Biologie
,
Chemie und Pharmazie
,
Medizin
,
Allgemeine Naturwissenschaft
,
Physik
Notizen:
[Auszug] AZT, after intracellular phosphorylation to AZT triphosphate, competitively inhibits reverse transcriptase with regard to thymidine triphosphate11, whereas mammalian DNA polymerases do not readily accept AZT triphosphate as substrate. AZT effectively inhibits infectivity and cytopathic effects of ...
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1038/323467a0
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