Publication Date:
2000-08-12
Description:
According to researchers who gathered here at a high-powered summit this month, toxicology may be on the verge of changing the way it collects raw data--adopting a process that could reduce animal use and improve test results. The new approach, called "toxicogenomics," uses DNA arrays to profile gene expression in cells exposed to test compounds. But some leaders in the field warn against rushing too quickly to embrace DNA tests, which are still difficult to interpret.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lovett, R A -- New York, N.Y. -- Science. 2000 Jul 28;289(5479):536-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10939962" target="_blank"〉PubMed〈/a〉
Keywords:
Animal Testing Alternatives
;
Animals
;
*Gene Expression Profiling
;
Humans
;
*Oligonucleotide Array Sequence Analysis
;
Peroxisome Proliferators/toxicity
;
Toxicity Tests/*methods
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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