ISSN:
1072-8368
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Medicine
Notes:
[Auszug] Here we show that, as a consequence of binding the drug trifluoperazine, a major conformational movement occurs in Ca2+-calmodulin (CaM). The tertiary structure changes from an elongated dumb-bell, with exposed hydrophobic surfaces, to a compact globular form which can no longer interact with its ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/nsb1194-795
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