ISSN:
1420-9071
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary A new series of compounds structurally related to the potential antidepressant tandamine, i.e., the 1-alkyl-1,2,3,4-tetrahydrocarbazole-1-ethanamines, inhibit the noradrenaline uptake mechanism and are relatively ineffective in inhibiting the serotonin uptake mechanism in vivo. The potency of the most effective compound (9-ethyl-N,N, 1-trimethyl-1,2,3,4-tetrahydrocarbazole is similar to that of desimipramine and is of potential use in the treatment of endogenously depressed patients.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01936753
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