ISSN:
0749-1581
Keywords:
viscosity
;
polarity
;
EPR
;
animal tumors
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Quantitative measurements of the viscosity of a non-vascular pharmacological compartment in a living animal are presented. Using novel, very low-frequency electron paramagnetic resonance spectroscopy, capable of measurements in humans, novel analytical techniques and partially deuterated spin probes, the viscosity of the body water of murine fibrosarcomas implanted in the leg of a living animal were measured. The average viscosity was 1.9 ± 0.2 cP. Variation of the viscosity with tumor size and histology did not appear to be significant.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260331322
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