Publication Date:
2015-07-24
Description:
Article DOT1L is an anti-cancer therapeutic target in leukaemia but has a poorly understood role in solid tumours. Here the authors show that DOT1L expression is associated with poor survival and aggressive cancers by helping to epigenetically activate the epithelial-mesenchymal transition during breast cancer progression. Nature Communications doi: 10.1038/ncomms8821 Authors: Min-Hyung Cho, Ji-Hye Park, Hee-Joo Choi, Mi-Kyung Park, Hee-Young Won, Yeon-Ji Park, Chang Hoon Lee, Seung-Hyun Oh, Young-Soo Song, Hyun Sung Kim, Young-Ha Oh, Jeong-Yeon Lee, Gu Kong
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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