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  • 1
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    In:  Bull. Seism. Soc. Am., London, Army Corps of Engineers, Woodward-Clyde Consultants, vol. 72, no. 4, pp. S367-S392, pp. 1013, (ISBN: 0-12-018847-3)
    Publication Date: 1982
    Keywords: Earthquake precursor: prediction research ; JAPAN ; BSSA
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  • 2
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    In:  Earthquake Notes, Luxembourg, Conseil de l'Europe, vol. 51, no. 3, pp. 71, pp. 1006, (ISSN: 1340-4202)
    Publication Date: 1981
    Keywords: Seismology ; Earthquake ; Source
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  • 3
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    In:  Eos, Trans., Am. Geophys. Un., Warszawa, Polish Geothermal Association, vol. 76, no. 6, pp. 49, pp. B05406, (ISSN: 1340-4202)
    Publication Date: 1995
    Keywords: Earthquake ; Review article
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  • 4
    Publication Date: 2013-11-30
    Description: We investigate the differential effects of metal cooling and galactic stellar winds on the cosmological formation of individual galaxies with three sets of cosmological, hydrodynamical zoom simulations of 45 haloes in the mass range 10 11  〈 M halo  〈 10 13 M . Models including both galactic winds and metal cooling (i) suppress early star formation at z 1 and predict reasonable star formation histories for galaxies in present-day haloes of 10 12 M , (ii) produce galaxies with high cold gas fractions (30–60 per cent) at high redshift, (iii) significantly reduce the galaxy formation efficiencies for haloes ( M halo 10 12 M ) at all redshifts in overall good agreement with recent observational data and constraints from abundance matching, (iv) result in high-redshift galaxies with reduced circular velocities in agreement with the observed Tully–Fisher relation at z  ~ 2 and (v) significantly increase the sizes of low-mass galaxies ( M stellar 3 10 10 M ) at high redshift resulting in a weak size evolution – a trend in agreement with observations. However, the low-redshift ( z  〈 0.5) star formation rates of more massive galaxies are higher than observed (up to 10 times). No tested model predicts the observed size evolution for low-mass and high-mass galaxies simultaneously. Without winds the sizes of low-mass galaxies evolve rapidly, and with winds the size evolution of massive galaxies is too weak. Due to the delayed onset of star formation in the wind models, the metal enrichment of gas and stars is delayed and agrees well with observational constraints. Metal cooling and stellar winds are both found to increase the ratio of in situ formed to accreted stars – the relative importance of dissipative versus dissipationless assembly. For halo masses below ~10 12 M , this is mainly caused by less stellar accretion and compares well to predictions from semi-analytical models and but differs from abundance matching models as the in situ formed fractions of stellar mass are still too low in the simulations. For higher masses, however, the fraction of in situ stars is overpredicted due to the unrealistically high star formation rates at low redshifts.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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  • 5
    Publication Date: 2016-04-13
    Description: A continuous succession of the upper part of the Alba Formation is recorded in the Vegas de Sotres section in the Cantabrian Mountains, northern Spain. This section contains slightly shallower-water facies than elsewhere and as a result is particularly rich in foraminifers. Characterization of the late Visean to Serpukhovian interval in coeval deeper water settings is accomplished by means of integrating conodont, ammonoid and foraminiferal data. The foraminiferal assemblages recorded in units 1–4 of the Alba Formation enabled correlation with the Russian substages in the Moscow Basin, Urals and Donets Basin. The upper part of the Canalón Member (unit 1) is correlated with the Venevian, the lower part of unit 2 is correlated with the Tarusian, and the Steshevian is recognized in the middle and upper part of unit 2. Most of unit 3 is correlated with the Protvian and is equivalent to the E2a ammonoid zone. The youngest Millaró Member (unit 4) contains undiagnostic foraminifers and lies within the Gnathodus truyolsi Conodont Zone equivalent to the E2b/E2c ammonoid zones. The base of the Serpukhovian is defined on the first occurrence of the conodont Lochriea ziegleri . Slightly below this horizon are recorded Neoarchaediscus parvus, N . aff. N . postrugosus, Biseriella paramoderata, Asteroarchaediscus rugosus, Howchinia hemisphaerica and Rectoendothyra latiformis . At the Visean/Serpukhovian (V/S) boundary, species of Tubispirodiscus are recorded and just above, the presence of Asteroarchaediscus baschkiricus is confirmed. The late Serpukhovian is characterized by the occurrence of diverse Eostaffella pseudostruvei, E . sp. cf. E. postmosquensis, Eostaffellina " protvae ", Eost. actuosa and Plectostaffella varvariensis . Two new genera and four new species are described: Janischewskina gibshmanae n. sp., Endostaffellopsis umbilicata n. gen. n. sp., Vachardites spinosus n. gen. n. sp., V. priscelloides n. gen. n. sp.
    Print ISSN: 0096-1191
    Topics: Geosciences
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  • 6
    Publication Date: 1993-07-23
    Description: The 25 April 1992 magnitude 7.1 Cape Mendocino thrust earthquake demonstrated that the North America-Gorda plate boundary is seismogenic and illustrated hazards that could result from much larger earthquakes forecast for the Cascadia region. The shock occurred just north of the Mendocino Triple Junction and caused strong ground motion and moderate damage in the immediate area. Rupture initiated onshore at a depth of 10.5 kilometers and propagated up-dip and seaward. Slip on steep faults in the Gorda plate generated two magnitude 6.6 aftershocks on 26 April. The main shock did not produce surface rupture on land but caused coastal uplift and a tsunami. The emerging picture of seismicity and faulting at the triple junction suggests that the region is likely to continue experiencing significant seismicity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Oppenheimer, D -- Eaton, J -- Jayko, A -- Lisowski, M -- Marshall, G -- Murray, M -- Simpson, R -- Stein, R -- Beroza, G -- Magee, M -- Carver, G -- Dengler, L -- McPherson, R -- Gee, L -- Romanowicz, B -- Gonzalez, F -- Li, W H -- Satake, K -- Somerville, P -- Valentine, D -- New York, N.Y. -- Science. 1993 Jul 23;261(5120):433-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17770022" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
    Publication Date: 2014-05-09
    Description: Limited evidence exists that humans mount a mutation-specific T cell response to epithelial cancers. We used a whole-exomic-sequencing-based approach to demonstrate that tumor-infiltrating lymphocytes (TIL) from a patient with metastatic cholangiocarcinoma contained CD4+ T helper 1 (T(H)1) cells recognizing a mutation in erbb2 interacting protein (ERBB2IP) expressed by the cancer. After adoptive transfer of TIL containing about 25% mutation-specific polyfunctional T(H)1 cells, the patient achieved a decrease in target lesions with prolonged stabilization of disease. Upon disease progression, the patient was retreated with a 〉95% pure population of mutation-reactive T(H)1 cells and again experienced tumor regression. These results provide evidence that a CD4+ T cell response against a mutated antigen can be harnessed to mediate regression of a metastatic epithelial cancer.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tran, Eric -- Turcotte, Simon -- Gros, Alena -- Robbins, Paul F -- Lu, Yong-Chen -- Dudley, Mark E -- Wunderlich, John R -- Somerville, Robert P -- Hogan, Katherine -- Hinrichs, Christian S -- Parkhurst, Maria R -- Yang, James C -- Rosenberg, Steven A -- Intramural NIH HHS/ -- New York, N.Y. -- Science. 2014 May 9;344(6184):641-5. doi: 10.1126/science.1251102.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Surgery Branch, National Cancer Institute (NCI), National Institutes of Health, Bethesda, MD 20892, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24812403" target="_blank"〉PubMed〈/a〉
    Keywords: Adaptor Proteins, Signal Transducing/*genetics ; Adoptive Transfer/*methods ; Adult ; Bile Duct Neoplasms/genetics/*therapy ; *Bile Ducts, Intrahepatic ; CD4-Positive T-Lymphocytes/*immunology ; Cholangiocarcinoma/genetics/*therapy ; Clinical Trials, Phase II as Topic ; Exome ; Female ; Humans ; Lymphocytes, Tumor-Infiltrating/*transplantation ; Mutation ; Receptor, ErbB-2/metabolism ; Th1 Cells/*transplantation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
    Publication Date: 2015-11-01
    Description: It is unknown whether the human immune system frequently mounts a T cell response against mutations expressed by common epithelial cancers. Using a next-generation sequencing approach combined with high-throughput immunologic screening, we demonstrated that tumor-infiltrating lymphocytes (TILs) from 9 out of 10 patients with metastatic gastrointestinal cancers contained CD4(+) and/or CD8(+) T cells that recognized one to three neo-epitopes derived from somatic mutations expressed by the patient's own tumor. There were no immunogenic epitopes shared between these patients. However, we identified in one patient a human leukocyte antigen-C*08:02-restricted T cell receptor from CD8(+) TILs that targeted the KRAS(G12D) hotspot driver mutation found in many human cancers. Thus, a high frequency of patients with common gastrointestinal cancers harbor immunogenic mutations that can potentially be exploited for the development of highly personalized immunotherapies.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tran, Eric -- Ahmadzadeh, Mojgan -- Lu, Yong-Chen -- Gros, Alena -- Turcotte, Simon -- Robbins, Paul F -- Gartner, Jared J -- Zheng, Zhili -- Li, Yong F -- Ray, Satyajit -- Wunderlich, John R -- Somerville, Robert P -- Rosenberg, Steven A -- Intramural NIH HHS/ -- New York, N.Y. -- Science. 2015 Dec 11;350(6266):1387-90. doi: 10.1126/science.aad1253. Epub 2015 Oct 29.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. ; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. sar@mail.nih.gov.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/26516200" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; CD8-Positive T-Lymphocytes/immunology ; Cell Line, Tumor ; Female ; Gastrointestinal Neoplasms/*genetics/*immunology/therapy ; HLA-C Antigens/genetics/immunology ; Humans ; Immunodominant Epitopes/genetics/immunology ; Immunotherapy/methods ; Lymphocytes, Tumor-Infiltrating/immunology ; Male ; Middle Aged ; Mutation ; Precision Medicine/methods ; Proto-Oncogene Proteins/genetics/immunology ; Receptors, Antigen, T-Cell/immunology ; ras Proteins/genetics/immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
    Publication Date: 2012-07-01
    Description: The foraminiferal superfamily Biseriamminaceae consists of the families Biseriamminidae (agglutinated wall) and Globivalvulinidae (secreted wall). The ancestral genus Biseriammina is endemic to the Urals, where its stratigraphic range is now extended from the Tournaisian into the early Visean, due to the inclusion of Lipinella within the genus. Other taxonomic changes in the Biseriamminidae include 1) suppression of Dzhamansorina , ? Admiranda, and ? Ulanbela under Koktjubina , 2) emendation of Koktjubina with descriptions of K. windsorensis n. comb., K. ? grata n. comb., and K. ? atlantica n. sp., and 3) establishment of a new genus Parabiseriella , composed of P. bristolensis n. comb. and P. moroccoensis n. sp. The genera Biseriella and Globivalvulina are the only Mississippian representatives of the Globivalvulinidae that evolved from the Biseriamminidae in the late Visean. Newly described species of those genera include B. scotica , B. paramoderata , and G. paraeogranulosa . The proposed phylogenetic lineage for the Mississippian Biseriamminaceae of Biseriammina –? Koktjubina/Parabiseriella–Biseriella – Globivalvulina developed in the Paleotethys followed by migration into the American Realm. Biseriamminidae have limited value as global biostratigraphic markers, unlike the Globivalvulinidae that have much greater potential, particularly from the Serpukhovian onward.
    Print ISSN: 0096-1191
    Topics: Geosciences
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  • 10
    Publication Date: 2015-07-31
    Description: We use semi-analytic models and cosmological merger trees to provide the initial conditions for multimerger numerical hydrodynamic simulations, and exploit these simulations to explore the effect of galaxy interaction and merging on star formation (SF). We compute numerical realizations of 12 merger trees from z  = 1.5 to 0. We include the effects of the large hot gaseous halo around all galaxies, following recent observations and predictions of galaxy formation models. We find that including the hot gaseous halo has a number of important effects. First, as expected, the star formation rate on long time-scales is increased due to cooling of the hot halo and refuelling of the cold gas reservoir. Secondly, we find that interactions do not always increase the SF in the long term. This is partially due to the orbiting galaxies transferring gravitational energy to the hot gaseous haloes and raising their temperature. Finally, we find that the relative size of the starburst, when including the hot halo, is much smaller than previous studies showed. Our simulations also show that the order and timing of interactions are important for the evolution of a galaxy. When multiple galaxies interact at the same time, the SF enhancement is less than when galaxies interact in series. All these effects show the importance of including hot gas and cosmologically motivated merger trees in galaxy evolution models.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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