ISSN:
1432-1041
Keywords:
Lormetazepam Memory
;
Geriatric volunteers Residual effects Psychometry
;
perception
;
motor control
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary 45 subjects aged over 65 years were randomly assigned to treatment with lormetazepam 0.5 mg or 1 mg or placebo. Mood and performance were measured with a battery of computerized tests. Subjects were tested before and after 1 and 8 nights of treatment. Pre- and post-treatment scores were analysed by a multivariate covariance technique, the pre-treatment score serving as covariate. The single and repeated doses of lormetazepam resulted in impairment of performance in a memory task, and the repeated dose administration impaired performance of a perceptual task. The single administration of a low dose gave an improvement in fine motor control. No change was found in the mood states of the subjects.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00315207
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