Publication Date:
2014-07-30
Description:
Pharmacological chaperones are small molecules that bind to proteins and stabilize them against thermal denaturation or proteolytic degradation, as well as assist or prevent certain protein–protein assemblies. These activities are being exploited for the development of treatments for diseases caused by protein instability and/or aberrant protein–protein interactions, such as those...
Print ISSN:
0027-8424
Electronic ISSN:
1091-6490
Topics:
Biology
,
Medicine
,
Natural Sciences in General
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