ISSN:
1573-8388
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract A peptide fragment with the 140–146 sequence of the main component of the surrace protein of the hepatitis B virus (HBsAG) and a number of its structural analogues have been synthesized by the classical method in solution. Conjugates of the peptides synthesized with bovine serum albumin and with a synthetic polypeptide analogue of polytuftsin have been obtained. The ability of the preparations to bind antibodies from the blood sera of hepatitis B patients has been studied. The possibility has been shown of their use for revealing antibodies to the heptatitis B virus in solid-phase enzyme-mediated immunoassay.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00630258
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