ISSN:
1420-9071
Keywords:
E coli
;
rat brain
;
glutamate
;
phosphonic analogues
;
glutamate decarboxylase
;
pyridoxal phosphate
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Among the phosphonic analogues of glutamic acid, only 4-amino-4-phosphono butyric acid, the compound which shows the highest affinity for pyridoxal phosphate, inhibits competitively bothEscherichia coli and rat brain glutamate decarboxylases. Phosphinothricin, 2-amino-4-(methylphosphino)butyric acid, is a strong inhibitor of the mammalian enzyme.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02007699
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