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  • 1
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Pharmacology 30 (1990), S. 169-195 
    ISSN: 0362-1642
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Soil Science Society of America journal 63 (1999), S. 425-432 
    ISSN: 1435-0661
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: N -ethyl-N′-(1-methyl-ethyl)-1,3,5-triazine-2,4-diamine] on the environment. A two-part study was conducted to evaluate: (i) atrazine release rate as a function of starch granule size, temperature, and water potential; and (ii) to compare the leaching of SE atrazine with the leaching of a commercial formulation in a calcareous soil. Atrazine release-rates from the starch granules were determined as a function of three granule sizes (1.40-0.85, 0.85-0.43, and 〈0.43 mm) at five temperatures (4, 10, 20, 25, and 35°C), and five matric potentials (0, -0.1, -0.5, -1.0, and -1.5 Mpa). Atrazine release-rates from the starch granules increased with decreasing granule size, increasing temperature, and increasing water potential. To evaluate leaching as function of atrazine formulation, each starch-encapsulated granule size, commercial formulation, and control treatment was replicated six times in irrigated soil columns (0.188 m2× 0.25 m). A pulse of bromide (10.7 kg Br- ha-1) and atrazine (1.7 kg ha-1) were coapplied to the soil columns and effluent concentrations monitored. Irrigation evens of 55 mm in 5 h were applied through drip emitters at 10-d intervals for 120 d for a total application of 11.5 pore volumes. Averaged bromide breakthrough curves for each soil column treatment were similar, which indicated that differences in the averaged atrazine mobilities were a result of formulation and not of heterogeneity in the soil matrix. Starch-encapsulated atrazine leaching decreased with increasing granule size; however, all SE formulations were less mobile than the commercial formulation. After 11.5 pore volumes and 120d, 〉:52% of the commercial atrazine had leached through the soil columns, compared with 〈38% for the smallest starch granule size and 11% for the largest granule. Starch-encapsulated formulations may be an effective tool for reducing pesticide leaching in calcareous soils.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-5036
    Keywords: Crop residues ; dry-matter yields ; Medicago sativa ; N mineralization ; 15N uptake ; Zea mays ; VAM fungi
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Legume crop residues serve as a source of nitrogen (N) for succeeding crops in low-input production systems, and characterizing the release of this N supports efforts to develop sound economic and environmental management practices. Nitrogen mineralization of 15N-labelled field crop residues was monitored in a Greenville sandy loam during a 140-day laboratory incubation at 25°C. Residue type strongly influenced the rate of N mineralization; decomposition rate constants were 0.283, 0.083, 0.00047 and 0.0014 day-1 for alfalfa (Medicago sativa L.) stover (above-ground plant parts), alfalfa roots, maize (Zea mays L.) stover (above-ground plant parts excluding cob and kernels) and maize roots, respectively. At the end of the incubation, 50% of alfalfa stover and 25% of alfalfa root residues N were mineralized, whereas these proportions were 8% for maize stover and 12% for root residues. Mineralization of 15N from alfalfa stover residues was also monitored in a greenhouse experiment to determine N availability during the growth of maize inoculated or not with vesicular-arbuscular mycorrhizal (VAM) fungi, and to evaluate the effects of the presence of plants on the decomposition of the residues. Stover and root dry matter yields were greatest for maize inoculated with VAM fungi and grown in residue-amended soil. At the final harvest, maize grown in residue-amended soils had accumulated 44% more dry matter and 40% more N than maize grown in unamended soils. Enhanced VAM colonization of roots inoculated with a mixture of three Glomus spp. increased the residue N accumulation in maize roots at 5 weeks after silking and at the final harvest. Alfalfa stover decomposed rapidly both in the presence and absence of maize plants, but the amount of 15N mineralized at the end of the experiment was influenced by the presence of living roots; 23% of the 15N in alfalfa stover residues was mineralized in soil without plants compared to about 38% when maize plants were present. These results suggest that N mineralization is enhanced by the presence of living roots.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 35 (1988), S. 529-535 
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The flammability characteristics of tris(2,3-dibromopropyl) phosphate (TRIS-BP), a known carcinogen, has been compared with other tris dibromo alkyl phosphates which show reduced mutagenic responses in experimental studies. The effectiveness of these alternative chemicals in releasing hydrogen bromide (HBr), a recognized combustion inhibitor, has been measured and the results compared with flammability evaluation of polyester fabrics treated with these chemicals. Results indicate that tris(2,3-dibromo-3,3-dimethyl propyl) phosphate, while having reduced mutagenicity and nephrotoxicity in comparison to TRIS-BP, exhibits excellent flame-retardant characteristics when applied to polyester fabrics. Meanwhile, other chemicals studied show comparable flame retardation to TRIS-BP, but with substantial reduced mutagenicity.
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 15 (1988), S. 157-161 
    ISSN: 0887-6134
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A gas chromatographic/mass spectrometric assay for quantifying two catechol estrogens, 2-hydroxyestradiol and 4-hydroxyestradiol, in microsomal preparations is described. The assay employs deuterium-labeled analogs of the catechol estrogens as internal standards and permits quantification of catechol estrogens, in microsomal incubations, at low (1-2) μM concentrations. The compounds are analyzed as their trimethylsilyl derivatives following separation by capillary gas chromatography.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 8 (1981), S. 244-251 
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The mass spectra of several thioether conjugates of the widely used analgesic, acetaminophen (4′-hydroxyacetanilide), have been recorded under various ionization conditions. Conjugates were obtained from both in vitro and in vivo sources and purified by high performance liquid chromatography. Some standards were chemically synthesized. Of the thioethers examined, only the methylthio and mercapturic acid conjrgates provided parent ions under electron impact conditions. In the chemical ionization mode, using isobutane as the reagent gas, the cysteinyl conjugate gave a pseudomolecular ion as well, although relatively large quantities (10-20 μg) of this amino acid adduct were required. Because of the highly polar nature and thermal instability of the cysteinyl and glutathionyl conjugates, these two thioethers were most successfully analyzed by field desorption techniques. Field desorption mass spectrometry was well suited for direct analysis of these two adducts where prominent [M]+., [MH]+ or [M+Na]+ ions were observed. Furthermore, by application of the field desorption/collision induced dissociation and linked (B/E) scan technique, structurally informative fragmentation patterns were generated. In addition, field desorption mass spectrometry was used successfully to characterize the glucuronide conjugate of acetaminophen but not the sulfate conjugate.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Preliminary results are reported for the quantitative determination of the antiarrhythmic agents quinidine and lidocaine in human plasma by combined isobutane chemical ionization mass spectrometry and stable isotope labeling. The concentration of monoethylglycinexylidide, a known metabolite of lidocaine, was also determined using this method. In the procedure used, stable isotope analogs of the materials to be determined were added to serial plasma samples. The plasma was then made basic and extracted with benzene. The residue after evaporation of the solvent was placed directly into the mass spectrometer via the direct insertion probe and the spectrum determined. In this manner the above named compounds could readily be quantitated without recourse to either derivitization or further purification.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 2 (1975), S. 23-30 
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: An ion doublet chemical ionization mass spectrometry technique was utilized for the rapid detection and elucidation of the structure of a new hydroxylated metabolite of the oral anticoagulant warfarin. This technique involves the use of a 50:50 mixture of stable isotope labeled and unlabeled drug. With this procedure ions found in the mass spectrum which are associated with the administered drug can be identified unambiguously. The unknown metabolite from rat liver microsomal preparations was identified as benzylic hydroxywarfarin by reincubating the microsomes with warfarin specifically labeled in the benzylic position and observing the subsequent loss of label in the product. The ion doublet technique was also employed in a single human study, and benzylic hydroxywarfarin was detected and identified.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Publication Date: 1984-03-01
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 10
    Publication Date: 1999-05-01
    Print ISSN: 0361-5995
    Electronic ISSN: 1435-0661
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by Wiley
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