ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The synthesis of the N-quaternary aminoalcohol 6 is described. Analogous to the aminoalcohols 1 and 2, 6 on treatment with alkali undergoes fission of the substituent at C(1) as a carbonyl compound, with formation of a N, N-dimethyl-1,2,3,4-tetrahydroisoquinolinium ion, which is further degraded to the corresponding o-vinyl-benzylamine (Scheme1). - As a by-product of a Bischler-Napieralski ring closure, we observed chlorination of an aromatic ring (yielding 19).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19750580639
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