ISSN:
1040-0397
Keywords:
Metallothioneins
;
Cathodic stripping voltammetry
;
Metal-binding proteins
;
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A cathodic stripping voltammetric method for the determination of metallothioneins (MT) is proposed. The procedure is based on the controlled adsorption of the protein on the mercury electrode after addition of an excess of CuII to the solution. The effects of accumulation time, adsorption potential and copper concentration have been examined and the analytical procedure has been optimized. Using an accumulation time of 300 s, a MT concentration of 0.2 nM can be detected.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/elan.1140080418
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