ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
The biological behavior of a new bioactive material composed of calcium-deficienthydroxyapatite, octacalcium phosphate, and β-tricalcium phosphate was investigated by in vitroindirect and direct cytotoxicity, cell adhesion and proliferation tests, and by in vivo subcutaneousand bone implantation in rats. The results of the in vitro studies showed that the material isbiocompatible and no cytotoxic. Slightly poorer initial cell adhesion and lower cell proliferationthan in control was observed, which were attributed to the reactivity and roughness of the materialsurface. In vivo results showed that the material is biodegradable and bioactive in bone tissue, butonly biocompatible and partially biodegradable in soft tissue
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/56/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.361-363.1127.pdf
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