ISSN:
1573-5001
Keywords:
B-DNA
;
3D NOE-NOE
;
Sugar conformation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Abstract The use of sugar restraints has been proven essential for assessing DNAstructures through molecular modeling studies. We present a new methodcombining 2D (COSY and NOESY) and 3D (NOESY-NOESY) experiments, whereconstraints on either the phase angles or the difference between phase anglesof two residues are obtained from comparison of 2D NOE H1′-H4′intensities and 3D NOE intensities containing the H1′-H4′transfer. All experiments lead to restraints that match, proving the validityof the method.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1018306210123
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