ALBERT

Description: Author(s): E. L. Starostin and G. H. M. van der Heijden [Phys. Rev. Lett. 107, 239801] Published Fri Dec 02, 2011

Description: Nano- and submicron-sized crystals are too small to contain inclusions and are, therefore, expected to have a higher internal quality compared to conventionally sized particles (several tens to hundreds of microns). Using electrospray crystallization, nano- and submicron-sized crystals can be easily produced. With the aid of electrospray crystallization, a mist of ultrafine solution droplets is generated and subsequent solvent evaporation leads to crystallization of submicron-sized crystals. Using cyclotrimethylene trinitramine (RDX) solutions in acetone, the conditions for a stable and continuous jet were established. At relatively small nozzle diameters and relatively low potential differences, hollow spheres of RDX crystals were observed. At a higher nozzle diameter and potential difference and in the region of a continuous jet, RDX crystals with an average size of around 400 nm could be produced. In order to test the quality of the submicron-sized energetic material, impact and friction sensitivity tests were carried out. The test results indicate that the submicron-sized product had reduced friction sensitivity, indicating a higher internal quality of the crystalline product. Electrospray crystallization is proposed as a method for creating high-quality submicron-sized crystals of the energetic material cyclotrimethylene trinitramine (RDX). The friction sensitivity of the obtained unagglomerated submicron-sized crystals was lower than that of conventional RDX, indicating that they have a better internal quality.

Description: Cancer is a disease in which cells accumulate genetic aberrations that are believed to confer a clonal advantage over cells in the surrounding tissue. However, the quantitative benefit of frequently occurring mutations during tumor development remains unknown. We quantified the competitive advantage of Apc loss, Kras activation, and P53 mutations in the mouse intestine. Our findings indicate that the fate conferred by these mutations is not deterministic, and many mutated stem cells are replaced by wild-type stem cells after biased, but still stochastic events. Furthermore, P53 mutations display a condition-dependent advantage, and especially in colitis-affected intestines, clones harboring mutations in this gene are favored. Our work confirms the previously theoretical notion that the tissue architecture of the intestine suppresses the accumulation of mutated lineages.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vermeulen, Louis -- Morrissey, Edward -- van der Heijden, Maartje -- Nicholson, Anna M -- Sottoriva, Andrea -- Buczacki, Simon -- Kemp, Richard -- Tavare, Simon -- Winton, Douglas J -- Cancer Research UK/United Kingdom -- New York, N.Y. -- Science. 2013 Nov 22;342(6161):995-8. doi: 10.1126/science.1243148.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Cancer Research UK, Cambridge Institute, University of Cambridge, Robinson Way, Cambridge CB2 0RE, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24264992" target="_blank"〉PubMed〈/a〉

Description: Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk, Published online: 13 August 2018; doi:10.1038/s41467-018-05074-y The chromosome 15q25.1 locus is a leading susceptibility region for lung cancer. Here, the authors interrogate three GWAS cohorts with 42,901 individuals to investigate potential pathological pathways such as gated channel activity and neuroactive ligand receptor interaction in lung cancer etiology.

Description: In 2010, dry-season rainfall was low across Amazonia, with apparent similarities to the major 2005 drought. We analyzed a decade of satellite-derived rainfall data to compare both events. Standardized anomalies of dry-season rainfall showed that 57% of Amazonia had low rainfall in 2010 as compared with 37% in 2005 (〈/=-1 standard deviation from long-term mean). By using relationships between drying and forest biomass responses measured for 2005, we predict the impact of the 2010 drought as 2.2 x 10(15) grams of carbon [95% confidence intervals (CIs) are 1.2 and 3.4], largely longer-term committed emissions from drought-induced tree deaths, compared with 1.6 x 10(15) grams of carbon (CIs 0.8 and 2.6) for the 2005 event.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lewis, Simon L -- Brando, Paulo M -- Phillips, Oliver L -- van der Heijden, Geertje M F -- Nepstad, Daniel -- New York, N.Y. -- Science. 2011 Feb 4;331(6017):554. doi: 10.1126/science.1200807.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉School of Geography, University of Leeds, Leeds LS2 9JT, UK. s.l.lewis@leeds.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21292971" target="_blank"〉PubMed〈/a〉

Description: Atmospheric carbon dioxide records indicate that the land surface has acted as a strong global carbon sink over recent decades, with a substantial fraction of this sink probably located in the tropics, particularly in the Amazon. Nevertheless, it is unclear how the terrestrial carbon sink will evolve as climate and atmospheric composition continue to change. Here we analyse the historical evolution of the biomass dynamics of the Amazon rainforest over three decades using a distributed network of 321 plots. While this analysis confirms that Amazon forests have acted as a long-term net biomass sink, we find a long-term decreasing trend of carbon accumulation. Rates of net increase in above-ground biomass declined by one-third during the past decade compared to the 1990s. This is a consequence of growth rate increases levelling off recently, while biomass mortality persistently increased throughout, leading to a shortening of carbon residence times. Potential drivers for the mortality increase include greater climate variability, and feedbacks of faster growth on mortality, resulting in shortened tree longevity. The observed decline of the Amazon sink diverges markedly from the recent increase in terrestrial carbon uptake at the global scale, and is contrary to expectations based on models.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brienen, R J W -- Phillips, O L -- Feldpausch, T R -- Gloor, E -- Baker, T R -- Lloyd, J -- Lopez-Gonzalez, G -- Monteagudo-Mendoza, A -- Malhi, Y -- Lewis, S L -- Vasquez Martinez, R -- Alexiades, M -- Alvarez Davila, E -- Alvarez-Loayza, P -- Andrade, A -- Aragao, L E O C -- Araujo-Murakami, A -- Arets, E J M M -- Arroyo, L -- Aymard C, G A -- Banki, O S -- Baraloto, C -- Barroso, J -- Bonal, D -- Boot, R G A -- Camargo, J L C -- Castilho, C V -- Chama, V -- Chao, K J -- Chave, J -- Comiskey, J A -- Cornejo Valverde, F -- da Costa, L -- de Oliveira, E A -- Di Fiore, A -- Erwin, T L -- Fauset, S -- Forsthofer, M -- Galbraith, D R -- Grahame, E S -- Groot, N -- Herault, B -- Higuchi, N -- Honorio Coronado, E N -- Keeling, H -- Killeen, T J -- Laurance, W F -- Laurance, S -- Licona, J -- Magnussen, W E -- Marimon, B S -- Marimon-Junior, B H -- Mendoza, C -- Neill, D A -- Nogueira, E M -- Nunez, P -- Pallqui Camacho, N C -- Parada, A -- Pardo-Molina, G -- Peacock, J -- Pena-Claros, M -- Pickavance, G C -- Pitman, N C A -- Poorter, L -- Prieto, A -- Quesada, C A -- Ramirez, F -- Ramirez-Angulo, H -- Restrepo, Z -- Roopsind, A -- Rudas, A -- Salomao, R P -- Schwarz, M -- Silva, N -- Silva-Espejo, J E -- Silveira, M -- Stropp, J -- Talbot, J -- ter Steege, H -- Teran-Aguilar, J -- Terborgh, J -- Thomas-Caesar, R -- Toledo, M -- Torello-Raventos, M -- Umetsu, R K -- van der Heijden, G M F -- van der Hout, P -- Guimaraes Vieira, I C -- Vieira, S A -- Vilanova, E -- Vos, V A -- Zagt, R J -- England -- Nature. 2015 Mar 19;519(7543):344-8. doi: 10.1038/nature14283.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉School of Geography, University of Leeds, Leeds LS2 9JT, UK. ; 1] School of Geography, University of Leeds, Leeds LS2 9JT, UK. [2] Geography, College of Life and Environmental Sciences, University of Exeter, Rennes Drive, Exeter EX4 4RJ, UK. ; 1] Department of Life Sciences, Imperial College London, Silwood Park Campus, Buckhurst Road, Ascot, Berkshire SL5 7PY, UK. [2] School of Marine and Tropical Biology, James Cook University, Cairns, 4870 Queenland, Australia. ; Jardin Botanico de Missouri, Prolongacion Bolognesi Mz.e, Lote 6, Oxapampa, Pasco, Peru. ; Environmental Change Institute, School of Geography and the Environment, University of Oxford, Oxford OX1 3QK, UK. ; 1] School of Geography, University of Leeds, Leeds LS2 9JT, UK. [2] Department of Geography, University College London, Pearson Building, Gower Street, London WC1E 6BT, UK. ; School of Anthropology and Conservation, Marlowe Building, University of Kent, Canterbury CT1 3EH, UK. ; Servicios Ecosistemicos y Cambio Climatico, Jardin Botanico de Medellin, Calle 73 no. 51 D-14, C.P. 050010, Medellin, Colombia. ; Center for Tropical Conservation, Duke University, Box 90381, Durham, North Carolina 27708, USA. ; Biological Dynamics of Forest Fragment Project (INPA &STRI), C.P. 478, Manaus AM 69011-970, Brazil. ; 1] Geography, College of Life and Environmental Sciences, University of Exeter, Rennes Drive, Exeter EX4 4RJ, UK. [2] National Institute for Space Research (INPE), Av. Dos Astronautas, 1758, Sao Jose dos Campos, Sao Paulo 12227-010, Brazil. ; Museo de Historia Natural Noel Kempff Mercado, Universidad Autonoma Gabriel Rene Moreno, Casilla 2489, Av. Irala 565, Santa Cruz, Bolivia. ; Alterra, Wageningen University and Research Centre, PO Box 47, 6700 AA Wageningen, The Netherlands. ; UNELLEZ-Guanare, Programa de Ciencias del Agro y el Mar, Herbario Universitario (PORT), Mesa de Cavacas, Estado Portuguesa, 3350 Venezuela. ; Biodiversiteit en Ecosysteem Dynamica, University of Amsterdam, Postbus 94248, 1090 GE Amsterdam, The Netherlands. ; 1] Institut National de la Recherche Agronomique, UMR EcoFoG, Campus Agronomique, 97310 Kourou, French Guiana. [2] International Center for Tropical Botany, Department of Biological Sciences, Florida International University, Miami, Florida 33199, USA. ; Universidade Federal do Acre, Campus de Cruzeiro do Sul, Rio Branco, Brazil. ; INRA, UMR 1137 ''Ecologie et Ecophysiologie Forestiere'' 54280 Champenoux, France. ; Embrapa Roraima, Caixa Postal 133, Boa Vista, RR, CEP 69301-970, Brazil. ; Universidad Nacional San Antonio Abad del Cusco, Av. de la Cultura N degrees 733, Cusco, Peru. ; 1] School of Geography, University of Leeds, Leeds LS2 9JT, UK. [2] International Master Program of Agriculture, College of Agriculture and Natural Resources, National Chung Hsing University, Taichung 40227, Taiwan. ; Universite Paul Sabatier CNRS, UMR 5174 Evolution et Diversite Biologique, Batiment 4R1, 31062 Toulouse, France. ; Northeast Region Inventory and Monitoring Program, National Park Service, 120 Chatham Lane, Fredericksburg, Virginia 22405, USA. ; Andes to Amazon Biodiversity Program, Puerto Maldonado, Madre de Dios, Peru. ; Universidade Federal do Para, Centro de Geociencias, Belem, CEP 66017-970 Para, Brazil. ; Universidade do Estado de Mato Grosso, Campus de Nova Xavantina, Caixa Postal 08, CEP 78.690-000, Nova Xavantina MT, Brazil. ; Department of Anthropology, University of Texas at Austin, SAC Room 5.150, 2201 Speedway Stop C3200, Austin, Texas 78712, USA. ; Department of Entomology, Smithsonian Institution, PO Box 37012, MRC 187, Washington DC 20013-7012, USA. ; Cirad, UMR Ecologie des Forets de Guyane, Campus Agronomique, 97310 Kourou, French Guiana. ; 1] School of Geography, University of Leeds, Leeds LS2 9JT, UK. [2] Instituto de Investigaciones de la Amazonia Peruana, Av. A. Jose Quinones km 2.5, Iquitos, Peru. ; World Wildlife Fund, 1250 24th Street NW, Washington DC 20037, USA. ; Centre for Tropical Environmental and Sustainability Science (TESS) and School of Marine and Environmental Sciences, James Cook University, Cairns, Queensland 4878, Australia. ; Instituto Boliviano de Investigacion Forestal, C.P. 6201, Santa Cruz de la Sierra, Bolivia. ; National Institute for Research in Amazonia (INPA), C.P. 478, Manaus, Amazonas, CEP 69011-970, Brazil. ; 1] FOMABO, Manejo Forestal en las Tierras Tropicales de Bolivia, Sacta, Bolivia. [2] Escuela de Ciencias Forestales (ESFOR), Universidad Mayor de San Simon (UMSS), Sacta, Bolivia. ; Universidad Estatal Amazonica, Facultad de Ingenieria Ambiental, Paso lateral km 2 1/2 via Napo, Puyo, Pastaza, Ecuador. ; National Institute for Research in Amazonia (INPA), C.P. 2223, 69080-971, Manaus, Amazonas, Brazil. ; Universidad Autonoma del Beni, Campus Universitario, Av. Ejercito Nacional, Riberalta, Beni, Bolivia. ; 1] Instituto Boliviano de Investigacion Forestal, C.P. 6201, Santa Cruz de la Sierra, Bolivia. [2] Forest Ecology and Forest Management Group, Wageningen University, PO Box 47, 6700 AA Wageningen, The Netherlands. ; 1] Center for Tropical Conservation, Duke University, Box 90381, Durham, North Carolina 27708, USA. [2] The Field Museum, 1400 South Lake Shore Drive, Chicago, Illinois 60605-2496, USA. ; Forest Ecology and Forest Management Group, Wageningen University, PO Box 47, 6700 AA Wageningen, The Netherlands. ; Universidad Nacional de la Amazonia Peruana, Iquitos, Loreto, Peru. ; Instituto de Investigaciones para el Desarrollo Forestal (INDEFOR), Universidad de Los Andes, Facultad de Ciencias Forestales y Ambientales, Conjunto Forestal, C.P. 5101, Merida, Venezuela. ; Iwokrama International Centre for Rainforest Conservation and Development, 77 High Street Kingston, Georgetown, Guyana. ; Museu Paraense Emilio Goeldi, Av. Magalhaes Barata, 376 - Sao Braz, CEP 66040-170, Belem PA, Brazil. ; UFRA, Av. Presidente Tancredo Neves 2501, CEP 66.077-901, Belem, Para, Brazil. ; Museu Universitario, Universidade Federal do Acre, Rio Branco AC 69910-900, Brazil. ; European Commission - DG Joint Research Centre, Institute for Environment and Sustainability, Via Enrico Fermi 274, 21010 Ispra, Italy. ; 1] Naturalis Biodiversity Center, PO Box, 2300 RA, Leiden, The Netherlands. [2] Ecology and Biodiversity Group, Utrecht University, PO Box 80084, 3508 TB Utrecht, The Netherlands. ; Museo de Historia Natural Alcide D'Orbigny, Av. Potosi no 1458, Cochabamba, Bolivia. ; 1] School of Earth and Environmental Science, James Cook University, Cairns, Queensland 4870, Australia. [2] Centre for Tropical Environmental and Sustainability Science (TESS) and School of Marine and Tropical Biology, James Cook University, Cairns, Queensland 4878, Australia. ; 1] Northumbria University, School of Geography, Ellison Place, Newcastle upon Tyne, Newcastle NE1 8ST, UK. [2] University of Wisconsin, Milwaukee, Wisconsin 53202, USA. [3] Smithsonian Tropical Research Institute, Apartado Postal 0843-03092, Panama, Republic of Panama. ; Van der Hout Forestry Consulting, Jan Trooststraat 6, 3078 HP Rotterdam, The Netherlands. ; Universidade Estadual de Campinas, NEPAM, Rua dos Flamboyants, 155- Cidade Universitaria Zeferino Vaz, Campinas, CEP 13083-867, Sao Paulo, Brazil. ; 1] Universidad Autonoma del Beni, Campus Universitario, Av. Ejercito Nacional, Riberalta, Beni, Bolivia. [2] Centro de Investigacion y Promocion del Campesinado, regional Norte Amazonico, C/ Nicanor Gonzalo Salvatierra N degrees 362, Casilla 16, Riberalta, Bolivia. ; Tropenbos International, PO Box 232, 6700 AE Wageningen, The Netherlands.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25788097" target="_blank"〉PubMed〈/a〉

Description: Author(s): M. Cox, E. H. M. van der Heijden, P. Janssen, and B. Koopmans Traps are localized, deep lying energetic states and are generally considered detrimental for organic semiconducting devices. In this work, we investigate their influence on the magnetic field sensitive current in organic devices, an effect often called organic magnetoresistance. Polymer thin films ... [Phys. Rev. B 89, 085201] Published Thu Feb 06, 2014

Description: Author(s): E. L. Starostin and G. H. M. van der Heijden We show that thin rectangular ribbons, defined as energy-minimizing configurations of the Sadowsky functional for narrow developable elastic strips, have a propensity to form spherical shapes in the sense that forceless solutions lie on a sphere. This has implications for ribbonlike objects in (bio)... [Phys. Rev. E 97, 023001] Published Thu Feb 08, 2018