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  • 1
    Publication Date: 2019
    Description: Egypt has one of the largest and fastest growing populations in the world. However, nearly 96% of the total land area is uninhabited desert and 96% of the population is concentrated around the River Nile valley and the Delta. This unbalanced distribution and dramatically rising population have caused severe socio-economic problems. In this research, 24 land use/land cover (LULC) maps from 1992 to 2015 were used to monitor LULC changes in the Nile Delta and quantify the rates and types of LULC transitions. The results show that 74,600 hectares of fertile agricultural land in the Nile Delta (Old Lands) was lost to urban expansion over the 24 year period at an average rate of 3108 ha year−1, whilst 206,100 hectares of bare land was converted to agricultural land (New Lands) at an average rate of 8588 ha year−1. A Cellular Automata-Markov (CA-Markov) integrated model was used to simulate future alternative LULC change scenarios. Under a Business as Usual scenario, 87,000 hectares of land transitioned from agricultural land to urban areas by 2030, posing a threat to the agricultural sector sustainability and food security in Egypt. Three alternative future scenarios were developed to promote urban development elsewhere, hence, with potential to preserve the fertile soils of the Nile Delta. A scenario which permitted urban expansion into the desert only preserved the largest amount of agricultural land in the Nile Delta. However, a scenario that encouraged urban expansion into the desert and adjacent to areas of existing high population density resulted in almost the same area of agricultural land being preserved. The alternative future scenarios are valuable for supporting policy development and planning decisions in Egypt and demonstrating that continued urban development is possible while minimising the threats to environmental sustainability and national food security.
    Electronic ISSN: 2072-4292
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Published by MDPI
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  • 2
    Publication Date: 2010-07-24
    Description: We report on the detection in southern Egypt of an impact crater 45 meters in diameter with a pristine rayed structure. Such pristine structures are typically observed on atmosphereless rocky or icy planetary bodies in the solar system. This feature and the association with an iron meteorite impactor and shock metamorphism provides a unique picture of small-scale hypervelocity impacts on Earth's crust. Contrary to current geophysical models, ground data indicate that iron meteorites with masses of the order of tens of tons can penetrate the atmosphere without substantial fragmentation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Folco, Luigi -- Di Martino, Mario -- El Barkooky, Ahmed -- D'Orazio, Massimo -- Lethy, Ahmed -- Urbini, Stefano -- Nicolosi, Iacopo -- Hafez, Mahfooz -- Cordier, Carole -- van Ginneken, Matthias -- Zeoli, Antonio -- Radwan, Ali M -- El Khrepy, Sami -- El Gabry, Mohamed -- Gomaa, Mahomoud -- Barakat, Aly A -- Serra, Romano -- El Sharkawi, Mohamed -- New York, N.Y. -- Science. 2010 Aug 13;329(5993):804. doi: 10.1126/science.1190990. Epub 2010 Jul 22.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Museo Nazionale dell'Antartide Universita di Siena, Via Laterina 8, 53100 Siena, Italy. folco@unisi.it〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20651117" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2014-11-22
    Description: Nucleoside reverse transcriptase inhibitors (NRTIs) are mainstay therapeutics for HIV that block retrovirus replication. Alu (an endogenous retroelement that also requires reverse transcriptase for its life cycle)-derived RNAs activate P2X7 and the NLRP3 inflammasome to cause cell death of the retinal pigment epithelium in geographic atrophy, a type of age-related macular degeneration. We found that NRTIs inhibit P2X7-mediated NLRP3 inflammasome activation independent of reverse transcriptase inhibition. Multiple approved and clinically relevant NRTIs prevented caspase-1 activation, the effector of the NLRP3 inflammasome, induced by Alu RNA. NRTIs were efficacious in mouse models of geographic atrophy, choroidal neovascularization, graft-versus-host disease, and sterile liver inflammation. Our findings suggest that NRTIs are ripe for drug repurposing in P2X7-driven diseases.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274127/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274127/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fowler, Benjamin J -- Gelfand, Bradley D -- Kim, Younghee -- Kerur, Nagaraj -- Tarallo, Valeria -- Hirano, Yoshio -- Amarnath, Shoba -- Fowler, Daniel H -- Radwan, Marta -- Young, Mark T -- Pittman, Keir -- Kubes, Paul -- Agarwal, Hitesh K -- Parang, Keykavous -- Hinton, David R -- Bastos-Carvalho, Ana -- Li, Shengjian -- Yasuma, Tetsuhiro -- Mizutani, Takeshi -- Yasuma, Reo -- Wright, Charles -- Ambati, Jayakrishna -- BB/J017345/1/Biotechnology and Biological Sciences Research Council/United Kingdom -- DP1 GM114862/GM/NIGMS NIH HHS/ -- DP1GM114862/DP/NCCDPHP CDC HHS/ -- K99 EY024336/EY/NEI NIH HHS/ -- K99EY024336/EY/NEI NIH HHS/ -- P30EY003040/EY/NEI NIH HHS/ -- R01 EY018350/EY/NEI NIH HHS/ -- R01 EY018836/EY/NEI NIH HHS/ -- R01 EY020672/EY/NEI NIH HHS/ -- R01 EY022238/EY/NEI NIH HHS/ -- R01 EY024068/EY/NEI NIH HHS/ -- R01EY001545/EY/NEI NIH HHS/ -- R01EY018350/EY/NEI NIH HHS/ -- R01EY018836/EY/NEI NIH HHS/ -- R01EY020672/EY/NEI NIH HHS/ -- R01EY022238/EY/NEI NIH HHS/ -- R01EY024068/EY/NEI NIH HHS/ -- T32HL091812/HL/NHLBI NIH HHS/ -- TL1 RR033172/RR/NCRR NIH HHS/ -- TL1 TR000115/TR/NCATS NIH HHS/ -- UL1 RR033173/RR/NCRR NIH HHS/ -- UL1 TR000117/TR/NCATS NIH HHS/ -- UL1RR033173/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 2014 Nov 21;346(6212):1000-3. doi: 10.1126/science.1261754.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY 40536, USA. Department of Physiology, University of Kentucky, Lexington, KY 40536, USA. ; Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY 40536, USA. Department of Microbiology, Immunology, and Human Genetics, University of Kentucky, Lexington, KY 40536, USA. Department of Biomedical Engineering, University of Kentucky, Lexington, KY 40536, USA. ; Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY 40536, USA. ; Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY 40536, USA. Angiogenesis Lab, Institute of Genetics and Biophysics, CNR, Naples, Italy. ; Experimental Transplantation and Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. ; School of Biosciences, Cardiff University, Cardiff CF10 3AX, UK. ; Immunology Research Group, University of Calgary, Calgary, Alberta T2N 4N1, Canada. ; Chapman University School of Pharmacy, 9401 Jeronimo Road, Harry and Diane Rinker Health Science Campus, Irvine, CA 92618, USA. ; Departments of Pathology and Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA. ; Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY 40536, USA. Department of Physiology, University of Kentucky, Lexington, KY 40536, USA. jamba2@email.uky.edu.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25414314" target="_blank"〉PubMed〈/a〉
    Keywords: Alu Elements ; Animals ; Anti-Inflammatory Agents, Non-Steroidal/*pharmacology/therapeutic use ; Apoptosis/drug effects ; Carrier Proteins/metabolism ; Caspase 1/metabolism ; Choroidal Neovascularization/drug therapy ; Disease Models, Animal ; Geographic Atrophy/drug therapy ; Graft vs Host Disease/drug therapy ; Hepatitis/drug therapy ; Inflammasomes/*drug effects ; Liver/drug effects ; Mice ; Receptors, Purinergic P2X7/metabolism ; Retinal Pigment Epithelium/drug effects/metabolism/physiology ; Reverse Transcriptase Inhibitors/*pharmacology/therapeutic use
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 2019
    Description: Detection and monitoring land use/land cover (LULC) changes using historical multi-temporal remote sensing data is greatly important for providing an effective and robust assessment of the human-induced impacts on the environmental conditions. It is extremely recommended for LULC studies related to evaluating the sustainability of changing areas over time. The agricultural sector in Egypt is one of the crucial pillars of the national economy. The amount of traditional agricultural land (Old Lands) in the Nile Delta had a significant decline over the past few decades due to urban encroachment. Consequently, several land reclamation initiatives and policies have been adopted by the Egyptian government to expand agricultural land in desert areas (New Lands) adjacent to both fringes of the Nile delta. Tiba district is one of those newly reclaimed areas located in the western Nile Delta of Egypt with a total area of 125 km2. The primary objective of this article was to identify, monitor and quantify historical LULC changes in Tiba district using historical multi-temporal Landsat imageries for six different dates acquired from 1988 to 2018. The temporal and historical changes that occurred were identified using supervised maximum likelihood classification (MLC) approach. Three major LULC classes were distinguished and mapped: (1) Agricultural land; (2) barren land; and (3) urban land. In 1988, Tiba district was 100% barren land; however, during the 1990s, the governmental reclamation projects have led to significant changes in LULC. The produced LULC maps from performing the MLC demonstrated that Tiba district had experienced significant agricultural land expansion from 0% in 1988 to occupy 84% in 2018, whilst, barren land area has decreased from 100% in 1988 to occupy only 7% in 2018. This reflects the successful governmental initiatives for agricultural expansion in desert areas located in the western Nile Delta of Egypt.
    Electronic ISSN: 2077-0472
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by MDPI
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Plant breeding 101 (1988), S. 0 
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Three pot experiments were earned our to investigate the variation among geographic accessions of Orobanche crenata Forsk. in their ability to attack different stocks of Vicia faba L. Orobanche accessions were quite different in their influence on the performance of genetic lines of the host. However, host parasite relationships appeared to be dependent upon environmental conditions. The usefulness or host genotypes for differentiating between parasite accessions was rather limited. The number of Orobanche shoots per host plant does not appear 10 be a precise indicator of host tolerance although it has been frequently used for this purpose.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Plant breeding 100 (1988), S. 0 
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Six populations of faba bean (Vicia faba L.) were developed through various selection schemes to examine the influence of selection In improving tolerance to Orobanche crenata (Forsk.) in local faba bean stocks. All populations trace their origin to 209 farmers’ seed lots that were collected from Egypt. The entries of each population were grown during the 1982/1983 season in the Orobanche nursery located at Giza in Egypt. Comparison among means of the selected, populations showed that more progress in improving Orobanche tolerance could be achieved from combined selection between and within lots. Between-lots selection was less efficient than single-plant selection. Results, of this study show that considerable progress could be achieved from selection for Orobanche tolerance in local faba bean germplasm. There was sufficient residual genetic variation in the selected populations to expect substantial progress from further selection for most tolerance traits.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    The @International Journal Of Applied Radiation And Isotopes 20 (1969), S. 871-872+IN9-IN10+873 
    ISSN: 0020-708X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Physics
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    The @International Journal Of Applied Radiation And Isotopes 22 (1971), S. 561-565 
    ISSN: 0020-708X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Physics
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    The @International Journal Of Applied Radiation And Isotopes 32 (1981), S. 97-99 
    ISSN: 0020-708X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Physics
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    The @International Journal Of Applied Radiation And Isotopes 35 (1984), S. 693-694 
    ISSN: 0020-708X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Physics
    Type of Medium: Electronic Resource
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