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  • 1
    Publication Date: 2024-03-29
    Description: Health and well-being is best understood in terms of a combination of biological, psychological, and social factors. But how ‘social’ is the biopsychosocial model when applied to mental health and rehabilitation? Psychology has traditionally viewed health as being determined by individual behavior. An integrative psychological approach is required to draw understanding from sociology, social psychology, and politics to consider how wider systemic, structural, and contextual factors impact on health behavior and outcomes. This e-book is dedicated to examining collective and community approaches to well-being and rehabilitation. In particular, the articles contained within this e-book are seeking to understand how social integration, social groups, social identity, and social capital influence health, well-being, and rehabilitation outcomes.
    Keywords: BF1-990 ; Q1-390 ; social support ; Well-being ; Health ; Rehabilitation ; Social identity ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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  • 2
    Publication Date: 2019
    Description: 〈p〉The human brain is a complex dynamical system, and how cognition emerges from spatiotemporal patterns of regional brain activity remains an open question. As different regions dynamically interact to perform cognitive tasks, variable patterns of partial synchrony can be observed, forming chimera states. We propose that the spatial patterning of these states plays a fundamental role in the cognitive organization of the brain and present a cognitively informed, chimera-based framework to explore how large-scale brain architecture affects brain dynamics and function. Using personalized brain network models, we systematically study how regional brain stimulation produces different patterns of synchronization across predefined cognitive systems. We analyze these emergent patterns within our framework to understand the impact of subject-specific and region-specific structural variability on brain dynamics. Our results suggest a classification of cognitive systems into four groups with differing levels of subject and regional variability that reflect their different functional roles.〈/p〉
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
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  • 3
    Publication Date: 2000-06-10
    Description: HIV-1 sequences were analyzed to estimate the timing of the ancestral sequence of the main group of HIV-1, the strains responsible for the AIDS pandemic. Using parallel supercomputers and assuming a constant rate of evolution, we applied maximum-likelihood phylogenetic methods to unprecedented amounts of data for this calculation. We validated our approach by correctly estimating the timing of two historically documented points. Using a comprehensive full-length envelope sequence alignment, we estimated the date of the last common ancestor of the main group of HIV-1 to be 1931 (1915-41). Analysis of a gag gene alignment, subregions of envelope including additional sequences, and a method that relaxed the assumption of a strict molecular clock also supported these results.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Korber, B -- Muldoon, M -- Theiler, J -- Gao, F -- Gupta, R -- Lapedes, A -- Hahn, B H -- Wolinsky, S -- Bhattacharya, T -- N01 AI 85338/AI/NIAID NIH HHS/ -- R01 AI 44596/AI/NIAID NIH HHS/ -- R01-HD37356/HD/NICHD NIH HHS/ -- etc. -- New York, N.Y. -- Science. 2000 Jun 9;288(5472):1789-96.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Los Alamos National Laboratory, Los Alamos, NM 87545, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10846155" target="_blank"〉PubMed〈/a〉
    Keywords: Acquired Immunodeficiency Syndrome/*epidemiology/transmission/*virology ; Africa/epidemiology ; Animals ; Confidence Intervals ; Consensus Sequence ; Disease Outbreaks ; Europe/epidemiology ; *Evolution, Molecular ; Genes, env ; HIV Envelope Protein gp160/genetics ; HIV-1/classification/*genetics ; Haiti/epidemiology ; Humans ; Likelihood Functions ; Pan troglodytes ; Phylogeny ; Simian Acquired Immunodeficiency Syndrome/transmission/virology ; Simian Immunodeficiency Virus/genetics ; Time Factors ; United States/epidemiology ; Zoonoses
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 2004-03-27
    Description: Heterosexual transmission accounts for the majority of human immunodeficiency virus-1 (HIV-1) infections worldwide, yet the viral properties that determine transmission fitness or outgrowth have not been elucidated. Here we show, for eight heterosexual transmission pairs, that recipient viruses were monophyletic, encoding compact, glycan-restricted envelope glycoproteins. These viruses were also uniquely sensitive to neutralization by antibody from the transmitting partner. Thus, the exposure of neutralizing epitopes, which are lost in chronic infection because of immune escape, appears to be favored in the newly infected host. This reveals characteristics of the envelope glycoprotein that influence HIV-1 transmission and may have implications for vaccine design.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Derdeyn, Cynthia A -- Decker, Julie M -- Bibollet-Ruche, Frederic -- Mokili, John L -- Muldoon, Mark -- Denham, Scott A -- Heil, Marintha L -- Kasolo, Francis -- Musonda, Rosemary -- Hahn, Beatrice H -- Shaw, George M -- Korber, Bette T -- Allen, Susan -- Hunter, Eric -- AI-40951/AI/NIAID NIH HHS/ -- AI-51231/AI/NIAID NIH HHS/ -- N01-85338/PHS HHS/ -- U01-AI-41530/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 2004 Mar 26;303(5666):2019-22.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294 USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15044802" target="_blank"〉PubMed〈/a〉
    Keywords: AIDS Vaccines ; Amino Acid Sequence ; Cohort Studies ; Epitopes/immunology ; Female ; Genes, env ; Glycosylation ; HIV Antibodies/*immunology ; HIV Envelope Protein gp120/chemistry/genetics/*immunology ; HIV Infections/*immunology/*transmission/virology ; HIV-1/genetics/*immunology/physiology ; Heterosexuality ; Humans ; Likelihood Functions ; Male ; Molecular Sequence Data ; Neutralization Tests ; Prospective Studies ; Viral Load ; Zambia
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 2016-05-14
    Description: We report on the second known locality for a large Malagasy eagle, Stephanoaetus mahery , that went extinct during the Holocene. This nearly complete skeleton comes from Ankilitelo Cave, a deep vertical pitfall shaft in the southwestern lowland portion of the island and in the subarid bioclimatic zone. The specimen was radiocarbon dated to 5550 ± 30 BP (Beta-415922). The holotype of this species comes from Ampasambazimba in the Central Highlands, part of the subhumid bioclimatic zone. The eagle remains from Ankilitelo Cave considerably expands the known geographical and ecological range of this species, which would have been a formidable predator and presumably feeding principally on lemurs.
    Print ISSN: 0959-6836
    Electronic ISSN: 1477-0911
    Topics: Geography , Geosciences
    Published by Sage
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  • 6
    Publication Date: 2001-12-01
    Print ISSN: 1431-2174
    Electronic ISSN: 1435-0157
    Topics: Geosciences
    Published by Springer
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  • 7
    ISSN: 1435-0157
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Résumé: La plupart des études de protection immédiate des forages conduites en aquifères en roches fissurées s'appuient sur l'hypothèse que l'aquifère est assimilable à un milieu poreux à l'échelle de la zone de protection immédiate. Des erreurs importantes peuvent résulter de l'application incorrecte de cette hypothèse. Certains auteurs ont proposé des critères théoriques et subjectifs pour déterminer dans quelles conditions l'approximation “milieu poreux” est acceptable. Toutefois, la plupart de ces critères requièrent un travail de terrain détaillé pour tester la validité de l'approximation “milieu poreux”. Nous avons expérimenté le modèle de Rouleau d'écoulement bidimensionnel en fractures discrètes coupléà un code de transport de particules pour déterminer dans quelles conditions l'approximation “Milieu poreux” est acceptable pour délimiter la zone d'influence d'un puits foré en roche fracturée. En particulier, nous avons recherché les effets de l'anisotrophie et de la densité de fractures sur la détermination de la zone d'influence. Nous avons trouvé que, m^me dans les aquifères intensément fracturés, la zone d'influence déterminée par le modèle d'écoulement en fracture est bien plus large que celle donnée par les modèles de type milieu poreux.
    Notes: Abstract: Most wellhead protection studies in fractured-rock aquifers rely on the assumption that the aquifer approximates a porous medium at the scale of the wellhead protection area. Significant errors can result if the assumption is incorrectly applied. Some authors have developed theoretical and subjective criteria for determining when the porous-media approximation is appropriate. Most of these criteria, however, require detailed field work to test the validity of the porous-media approximation. Experiments have been carried out with Roucleau's two-dimensional discrete fracture flow model coupled with a particle-tracking code to determine when the porous-media approximation is appropriate for delineating the capture zone of a well drilled in fractured rock. Specifically, the effects of anisotropy and fracture density on the capture-zone determination have been examined. It has been found that, even in densely fractured aquifers, the zone of contribution determined by the fracture-flow model is significantly larger than the capture zone determined by porous-media-based models.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Aequationes mathematicae 25 (1982), S. 67-76 
    ISSN: 1420-8903
    Keywords: Primary 39B05 ; Secondary 39A10, 33A15, 33A70
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Aequationes mathematicae 24 (1982), S. 319-319 
    ISSN: 1420-8903
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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  • 10
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