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  • 1
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    Gating of retinal transmission by afferent eye position and movement signals (1989)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1989-01-06
    Description: Vision in most vertebrates is an active process that requires the brain to combine retinal signals with information about eye movement. Eye movement information may feed forward from the motor control areas of the brain or feed back from the extrinsic eye muscles. Feedback signals elicited by passive eye movement selectively gate retinal outflow at the first relay, the dorsal lateral geniculate nucleus. The gating predominantly facilitates retinogeniculate transmission immediately after eye movement and inhibits transmission when a new steady-state eye position is achieved. These two gating effects are distributed in a complementary fashion across the dorsal lateral geniculate nucleus such that the spatiotemporal activity profile could contribute to object detection and localization.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lal, R -- Friedlander, M J -- EY-05116/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 1989 Jan 6;243(4887):93-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Neurobiology Research Center, University of Alabama, Birmingham 35294.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2911723" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials ; Afferent Pathways/*physiology ; Animals ; Cats ; *Eye Movements ; Retina/*physiology ; *Vision, Ocular ; Visual Pathways/*physiology ; Visual Perception
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Role of NO production in NMDA receptor-mediated neurotransmitter release in cerebral cortex (1994)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1994-02-18
    Description: L-Glutamate and norepinephrine are examples of a major excitatory neurotransmitter and a neuromodulator in the cerebral cortex, respectively. Little is known of how chemical signaling between the anatomically distinct chemical pathways occurs. Specific activation of the N-methyl-D-aspartate (NMDA) class of glutamate receptor in synaptosomal preparations from guinea pig cerebral cortex caused release of both of these chemicals, and this release was blocked by agents that inhibit nitric oxide (NO) production or remove NO from the extracellular space. Furthermore, neurotransmitter release correlated with cortical NO production after NMDA receptor stimulation. These results suggest that NO production and its extracellular movement may be links in the pathway from NMDA receptor activation to changes in chemical signaling in surrounding synaptic terminals in the cerebral cortex.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Montague, P R -- Gancayco, C D -- Winn, M J -- Marchase, R B -- Friedlander, M J -- EY05116/EY/NEI NIH HHS/ -- EY06714/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 1994 Feb 18;263(5149):973-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Neurobiology Research Center, University of Alabama at Birmingham 35294-0021.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7508638" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Oxidoreductases/antagonists & inhibitors ; Animals ; Arginine/analogs & derivatives/pharmacology ; Cerebral Cortex/drug effects/*metabolism ; Glutamates/*metabolism ; Glutamic Acid ; Guinea Pigs ; In Vitro Techniques ; Indazoles/pharmacology ; Male ; N-Methylaspartate/pharmacology ; Nitric Oxide/*metabolism ; Nitric Oxide Synthase ; Nitroarginine ; Norepinephrine/*metabolism ; Potassium Chloride/pharmacology ; Receptors, N-Methyl-D-Aspartate/*metabolism ; Synaptosomes/drug effects/*metabolism ; omega-N-Methylarginine
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Structure of physiologically identified X and Y cells in the cat's lateral geniculate nucleus (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: Horseradish peroxidase injected into 18 single, physiologically identified geniculate X and Y cells permitted a detailed morphological correlate to be determined for the physiological properties of each neuron. Class 1 morphological characteristics were associated with Y cells, class 3 with X cells, and class 2 structural traits were seen in both physiological types.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Friedlander, M J -- Lin, C S -- Sherman, S M -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1114-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451559" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cats ; Geniculate Bodies/*cytology/physiology ; Horseradish Peroxidase ; Interneurons/cytology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
    Electronic Resource
    Electronic Resource
    Effects of cold and heat on behavior and cerebellar function in goldfish (1976)
    Springer
    Journal of comparative physiology 112 (1976), S. 19-45 
    Details
    ISSN: 1432-1351
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A similar sequence of behavioral effects was observed for either cooling or heating; most effects occurred on changing temperature of entire fish or of only the cerebellum. On moderate heating or cooling, fish are hyperexcitable, spontaneously hyperactive; on further heating or cooling swimming is uncoordinated; when the subcerebellar structures are heated or cooled, equilibrium is disturbed; on further heating or cooling coma and respiratory failure ensue. Critical temperatures are modifiable by acclimation. The behavioral effects of cerebellectomy are additive with temperature effects on motor centers. Electrical activity of Purkinje neurons changes in the same thermal ranges as behavior. Inhibition via cerebellar interneurons is most sensitive and can be modified by acclimation. Ongoing activity increases with warming up to a blocking temperature; interspike interval histograms show pattern changes during warming. Activation via mossy fibers-granule cells is more sensitive than that via climbing fibers, and antidromic impulses are most resistant. A neuronal model based on inhibitory actions of Purkinje neurons on motor centers and parallel feedback excitatory pathways can explain both behavioral and electrical observations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00612674
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    Paper (German National Licenses)
    Fulltext
  • 5
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    Expression of an intrinsic growth strategy by mammalian retinal neurons. (1989)
    National Academy of Sciences
    Details
    Publication Date: 1989-09-01
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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