ISSN:
0006-3592
Keywords:
diffusion
;
gel
;
alginate
;
lactose
;
lactic acid
;
Chemistry
;
Biochemistry and Biotechnology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
A non-steady-state method has been used for determining the effective diffusion coefficient, De, and a distribution constant, Ki, of small molecules in alginate gel beads. A mathematical model based on Pick's law and includingexternal film diffusion resistance describe the diffusion process. Criticalexperimental parameters for the estimation of De and Ki, for both one- and two-parameter methods were the initial solute concentration in the bulk liquid, the void fraction inthe reactor, and the experimental starting point. In our analysis, the two-parameter method is preferable. Incorporation of an estimate of the film resistance into the overall model increased the estimated values of De significantly and improved the stability of the term over a range of reactor agitation rates. © 1995 John Wiley & Sons Inc.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bit.260470412
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