Publication Date:
2014-12-11
Description:
Article It is unclear how incoming influenza viruses counteract the cells’ first line of defence, the interferon (IFN) response. Here Liedmann et al. show that a distinct amino-acid motif in polymerases PB1 and PA, which are packaged in the viral particles, inhibit early IFN induction. Nature Communications doi: 10.1038/ncomms6645 Authors: Swantje Liedmann, Eike R. Hrincius, Cliff Guy, Darisuren Anhlan, Rüdiger Dierkes, Robert Carter, Gang Wu, Peter Staeheli, Douglas R. Green, Thorsten Wolff, Jonathan A. McCullers, Stephan Ludwig, Christina Ehrhardt
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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