ALBERT — All Library Books, journals and Electronic Records Telegrafenberg

Hits per page

hit 1 - 1 | 1 hit

Sorting

Electronic Resource

Asymmetric Synthesis of (1-Ferrocenylalkyl)amine and 1,1′-Bis(1-aminoalkyl)ferrocene Derivatives (1998)

Enders, Dieter ; Lochtman, René

Weinheim : Wiley-Blackwell

Liebigs Annalen 1998 (1998), S. 689-696

add to mindlist on the mindlist

Details

ISSN: 1434-193X

Keywords: Ferrocene ; Asymmetric synthesis ; Nucleophilic 1,2-addition ; Hydrazones ; Cleavage reactions ; Chemistry ; General Chemistry

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: The aldehydes 1 and 5 were converted to the corresponding SAMP hydrazones 2 and 6, respectively. Subsequent nucleophilic 1,2-addition of organolithium reagents to the C-N double bonds and cleavage of the N-N hydrazine bond using an excess of BH3·THF afforded (1-ferrocenylalkyl)amines (N-protection → 4) and 1,1′-bis(1-aminoalkyl)ferrocenes (N-protection → 8) in good overall yields (32-88%), with very high enantiomeric excesses (ee = 90-98%) and dl/meso ratios of up to 95:5.

Type of Medium: Electronic Resource

Permalink

	Location	Call Number	Expected	Availability

Others were also interested in ...

Paper (German National Licenses)

hit 1 - 1 | 1 hit