ISSN:
1617-4623
Keywords:
Aspergillus nidulans
;
Gene regulation
;
CCAAT box
;
amdR regulatory gene
;
Promoter
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary The amdR gene of Aspergillus nidulans regulates a number of structural genes in response to omega amino acid inducers. The site of action of the amdR product on expression of the amdS gene was investigated by studying the effects of changes in the 5′ region of amdS, generated in vitro, on the induction, and on responses of an amdS-lacZ fusion gene to an amdR c allele. A sequence was identified that is sufficient for amdR regulation and that shows identity with sequences involved in amdR regulation of the gatA and lam genes. This sequence includes a CCAAT sequence and it was shown that this sequence is an important element in setting the basal level of amdS expression.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00286184
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