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  • 1
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Marketing intelligence & planning 18 (2000), S. 135-144 
    ISSN: 0263-4503
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Explores the potential of a hybrid intelligent system in supporting marketing strategy development. First, a hybrid intelligent system for developing marketing strategy, called MarStra (developed by the author), is outlined. Then discusses the real-world tests of MarStra with marketing directors in five large UK companies. Empirical evidence from the companies involved indicates that MarStra is very helpful and useful in: providing strategic analysis guidance; coupling strategic analysis with managerial judgement; helping strategic thinking; dealing with fuzziness and uncertainty; and supporting group assessment of strategic marketing factors. The intelligent outputs generated by MarStra were reported to be surprisingly accurate, mostly sound and useful prompts.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0263-4503
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: A hybrid approach for integrating group Delphi, fuzzy logic and expert systems for developing marketing strategies is proposed in this paper. Within this approach, the group Delphi method is employed to help groups of managers undertake SWOT analysis. Fuzzy logic is applied to fuzzify the results of SWOT analysis. Expert systems are utilised to formulate marketing strategies based upon the fuzzified strategic inputs. In addition, guidelines are also provided to help users link the hybrid approach with managerial judgement and intuition. The effectiveness of the hybrid approach has been validated with MBA and MA marketing students. It is concluded that the hybrid approach is more effective in terms of decision confidence, group consensus, helping to understand strategic factors, helping strategic thinking, and coupling analysis with judgement, etc.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Marketing intelligence & planning 23 (2005), S. 77-88 
    ISSN: 0263-4503
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Purpose - The purpose of this paper is to: determine which criteria of the car insurance brokers' web sites are important or unimportant; establish how well those criteria are presented on the car insurance brokers' web sites; and find out whether the consumer's final decision to purchase the product is influenced by the web sites' characteristics, the price, etc. Design/methodology/approach - The evaluation method employed in this study is the extended web assessment method (EWAM), which is an evaluation tool specifically created for the assessment of electronic commerce applications. A double questionnaire survey has been undertaken to collect data from 28 finance advisers in an independent financial advisory firm in the UK. Findings - The preliminary findings suggest that the majority of the assessed web site criteria fall in the categories of "maintain strategy" and "no immediate improvement necessary" with certain web site features considered as "strategic overkill" or "improvement necessary". It is also found that the web sites are utilised as a tool for shopping around for quotes but the final purchase would be made by most consumers via the telephone. Research limitations/implications - It is important to mention that an empirical study with a sample of 28 insurance advisers in one financial advisory company can only reflect a limited picture of current practice in the UK car insurance brokers market. Therefore, the findings reported in this paper are tentative and preliminary. To test or confirm relevant findings reported here, further evaluation work with a larger number of assessors having different backgrounds may be necessary. Practical implications - While the majority of the assessed web site criteria fall in the "maintain strategy" and "no immediate improvement necessary" fields, efforts should be made by practitioners to improve site maps, site search, and insurers' details for quotes. Originality/value - This paper provides useful information for UK car insurance brokers and web sites developers.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Marketing intelligence & planning 17 (1999), S. 70-79 
    ISSN: 0263-4503
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: A framework for a hybrid intelligent support system is proposed, on the basis of a discussion of the main problems of current computer-based support systems and the roles for computer-based systems in developing marketing strategy. The objectives of the framework are: to integrate the strengths of different support techniques and technologies; to assist strategic analysis; to couple strategic analysis with managers' judgement; to help managers deal with uncertainty; and to aid strategic thinking. Within this framework, the benefits of different strategic analysis models are combined to offer enhanced support for a logical sequence of strategic analysis, while the advantages of diverse support techniques and technologies are integrated and fitted to support different aspects of the marketing strategy development process. As well as the theoretical basis for the proposed framework, the paper also examines the associated technical issues.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Marketing intelligence & planning 17 (1999), S. 209-216 
    ISSN: 0263-4503
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: A framework for a hybrid intelligent support system is proposed, on the basis of a discussion of the main problems of current computer-based support systems and the roles for computer-based systems in developing marketing strategy. The objectives of the framework are: to integrate the strengths of different support techniques and technologies; to assist strategic analysis; to couple strategic analysis with managers' judgement; to help managers deal with uncertainty; and to aid strategic thinking. Within this framework, the benefits of different strategic analysis models are combined to offer enhanced support for a logical sequence of strategic analysis, while the advantages of diverse support techniques and technologies are integrated and fitted to support different aspects of the marketing strategy development process. As well as the theoretical basis for the proposed framework, the paper also examines the associated technical issues.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Marketing intelligence & planning 22 (2004), S. 751-760 
    ISSN: 0263-4503
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: This paper reports a web-based intelligent system, called WebStra, for the formulation of marketing strategies and associated e-commerce strategies. In the paper, the architecture and functional components of the WebStra system are described. The system's effectiveness and efficiency are also evaluated. WebStra can be applied to support real-world strategic marketing decision making. It may also be used as a useful tool for training and consultancy purposes.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Bradford : Emerald
    European journal of marketing 34 (2000), S. 551-575 
    ISSN: 0309-0566
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Reports on an investigation of computer-based support for developing marketing strategy. First, on the basis of a literature study, the nature of marketing strategy development is clarified. The needs for computer-based support are identified. The status and underlying problems of existing computer-based information systems for developing marketing strategy are then examined. Finally, a mail questionnaire survey on computer-based support for developing marketing strategy is discussed. The major issues addressed in the survey were: managers' needs for computer-based support in developing marketing strategy; the current provision of computer-based information systems; and the gaps between the identified needs and current provision. It is believed that this was the first study to use a large-scale questionnaire survey to explore these issues. The findings provide important evidence and implications for both researchers and designers of computer-based support for marketing strategy development.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Industrial management & data systems 101 (2001), S. 132-141 
    ISSN: 0263-5577
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Computer Science , Economics
    Notes: An intelligent hybrid system, called GloStra (developed by the author), for developing global marketing strategy and associated Internet marketing strategy is reported in this paper. The hybrid system is built to integrate the strengths of expert systems, fuzzy logic, artificial neural networks and decision support technology; and to link the development of global marketing strategy with the formulation of associated Internet marketing strategy. In the paper, the system architecture, the functional modules of the hybrid system and other associated technical issues are addressed. The directions for further research in this field are also highlighted.
    Type of Medium: Electronic Resource
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  • 9
    Publication Date: 2017-10-24
    Description: ABIN1, an important immune regulator, has been shown to be involved in various cellular functions, such as immunity, development, tissue homeostasis and tumor progression. It inhibits TNF- and TLR-induced NF-κB signaling activation and the consequent gene expression. Despite its functional significance, the mechanism of ABIN1 in the regulation of various cellular functions remains unclear. In this study, we identified HDAC1, a key regulator of eukaryotic gene expression and many important cellular events, including cell proliferation, differentiation, cancer and immunity, as an interacting partner of ABIN1. The results showed that ABIN1 acts as a modulator to down-regulate HDAC1 ubiquitination via three different polyubiquitin linkages, thereby stabilizing HDAC1 by inhibiting its lysosomal and proteasomal degradation. Interestingly, the inhibitory function of ABIN1 required direct binding with HDAC1. Moreover, the level of p53, which is a tumor suppressor and a well-studied substrate of HDAC1, is under the regulation of ABIN1 via the modulation of HDAC1 levels, suggesting that ABIN1 is physiologically significant in tumor progression. This study has revealed a new function of ABIN1 in mediating HDAC1 modification and stability. This article is protected by copyright. All rights reserved
    Electronic ISSN: 0091-7419
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Published by Wiley
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  • 10
    Publication Date: 2018-02-12
    Print ISSN: 0022-2461
    Electronic ISSN: 1573-4803
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Published by Springer
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