Publication Date:
2010-11-12
Description:
Photoreceptors for visual perception, phototaxis or light avoidance are typically clustered in eyes or related structures such as the Bolwig organ of Drosophila larvae. Unexpectedly, we found that the class IV dendritic arborization neurons of Drosophila melanogaster larvae respond to ultraviolet, violet and blue light, and are major mediators of light avoidance, particularly at high intensities. These class IV dendritic arborization neurons, which are present in every body segment, have dendrites tiling the larval body wall nearly completely without redundancy. Dendritic illumination activates class IV dendritic arborization neurons. These novel photoreceptors use phototransduction machinery distinct from other photoreceptors in Drosophila and enable larvae to sense light exposure over their entire bodies and move out of danger.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026603/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉 〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026603/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Xiang, Yang -- Yuan, Quan -- Vogt, Nina -- Looger, Loren L -- Jan, Lily Yeh -- Jan, Yuh Nung -- R01 MH084234/MH/NIMH NIH HHS/ -- R37 NS040929/NS/NINDS NIH HHS/ -- R37 NS040929-11/NS/NINDS NIH HHS/ -- Howard Hughes Medical Institute/ -- England -- Nature. 2010 Dec 16;468(7326):921-6. doi: 10.1038/nature09576. Epub 2010 Nov 10.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Howard Hughes Medical Institute, Departments of Physiology, Biochemistry, and Biophysics, University of California San Francisco, San Francisco, California 94158, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21068723" target="_blank"〉PubMed〈/a〉
Keywords:
Animal Structures/cytology/metabolism/radiation effects
;
Animals
;
Avoidance Learning/physiology/radiation effects
;
Cells, Cultured
;
Dermis/metabolism/radiation effects
;
Drosophila Proteins/metabolism
;
Drosophila melanogaster/*anatomy & histology/cytology/physiology/*radiation
;
effects
;
Larva/anatomy & histology/cytology/radiation effects
;
*Light
;
Light Signal Transduction/radiation effects
;
Neurons/physiology/radiation effects
;
Photoreceptor Cells, Invertebrate/*metabolism/*radiation effects
;
Receptors, Cell Surface/metabolism
;
TRPC Cation Channels/metabolism
Print ISSN:
0028-0836
Electronic ISSN:
1476-4687
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
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