ISSN:
0030-493X
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Electron impact mass spectrometry of a range of amidines (R′NC(R)NHR′) including formamidines, acetamidines, benzamidines and tert-butylamidine, has been undertaken, and comparisons made of the fragmentation pathways followed by the different families of compounds. Fragmentation of all the molecular ions is characterized by skeletal carbon-nitrogen bond cleavage to form [R′NCR]+ and [R′NH]+ fragments, both of which are observed. For formamidines (R=H), the positive charge remains with the [R′NH]+ fragment which leads to the base peak at m/z93 corresponding to [R′NH2]+·. In contrast, for acetamidines and benzamidines the charge prefers to remain with the [R′NCR]+ fragment which gives the base peak for these compounds. The spectra of unsubstituted amidines (HNC(R)NH2) are characterized by cleavage of the carbon substituent from the NCN skeleton, [CN2H3]+ (m/z 43) being produced in all cases.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/oms.1210201006
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