ISSN:
1573-9171
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Conclusions 1. Starting with the esters of α,γ-dibromobutyric acid and primary amines, the synthesis of N-alkyIazetidine-2-carboxylic esters was extended to the simple amines. 2. The geminal nonequivalence of the diastereotopic protons and groups, observed in the NMR spectra of the N-alkylazetidine-2-carboxylic esters, is greater for the substituent on nitrogen than in the carbalkoxyl group. 3. The characteristic processes for the fragmentation of N-alkylazetidine-2-carboxylic esters under electron impact are the formation of amine fragments via cleavage of the substituent at C-2 and α-cleavage in the substituent on nitrogen.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00926302
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