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  • 1
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    Hemoglobin-AGE: a circulating marker of advanced glycosylation (1992)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1992-10-23
    Description: Advanced glycosylation end products (AGEs) form spontaneously from glucose-derived Amadori products and accumulate on long-lived tissue proteins. AGEs have been implicated in the pathogenesis of several of the complications of aging and diabetes, including atherosclerosis and renal disease. With the use of recently developed AGE-specific antibodies, an AGE-modified form of human hemoglobin has been identified. Termed hemoglobin-AGE (Hb-AGE), this modified species accounts for 0.42 percent of circulating hemoglobin in normal individuals but increases to 0.75 percent in patients with diabetes-induced hyperglycemia. In a group of diabetic patients treated with the advanced glycosylation inhibitor aminoguanidine, Hb-AGE levels decreased significantly over a 1-month period. Hemoglobin-AGE measurements may provide an index of long-term tissue modification by AGEs and prove useful in assessing the contribution of advanced glycosylation to a variety of diabetic and age-related complications.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Makita, Z -- Vlassara, H -- Rayfield, E -- Cartwright, K -- Friedman, E -- Rodby, R -- Cerami, A -- Bucala, R -- DK19655-15/DK/NIDDK NIH HHS/ -- New York, N.Y. -- Science. 1992 Oct 23;258(5082):651-3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Picower Institute for Medical Research, Manhasset, NY 11030.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1411574" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Aging/*blood ; Biomarkers/blood ; Diabetes Mellitus, Type 1/*blood/drug therapy ; Diabetes Mellitus, Type 2/*blood/drug therapy ; Enzyme-Linked Immunosorbent Assay ; Glycosylation ; Guanidines/*therapeutic use ; Hemoglobins/*analysis ; Humans ; Middle Aged
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Polarization observations with the Cosmic Background Imager (2004)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2004-10-09
    Description: Polarization observations of the cosmic microwave background with the Cosmic Background Imager from September 2002 to May 2004 provide a significant detection of the E-mode polarization and reveal an angular power spectrum of polarized emission showing peaks and valleys that are shifted in phase by half a cycle relative to those of the total intensity spectrum. This key agreement between the phase of the observed polarization spectrum and that predicted on the basis of the total intensity spectrum provides support for the standard model of cosmology, in which dark matter and dark energy are the dominant constituents, the geometry is close to flat, and primordial density fluctuations are predominantly adiabatic with a matter power spectrum commensurate with inflationary cosmological models.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Readhead, A C S -- Myers, S T -- Pearson, T J -- Sievers, J L -- Mason, B S -- Contaldi, C R -- Bond, J R -- Bustos, R -- Altamirano, P -- Achermann, C -- Bronfman, L -- Carlstrom, J E -- Cartwright, J K -- Casassus, S -- Dickinson, C -- Holzapfel, W L -- Kovac, J M -- Leitch, E M -- May, J -- Padin, S -- Pogosyan, D -- Pospieszalski, M -- Pryke, C -- Reeves, R -- Shepherd, M C -- Torres, S -- New York, N.Y. -- Science. 2004 Oct 29;306(5697):836-44. Epub 2004 Oct 7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Owens Valley Radio Observatory, California Institute of Technology, Pasadena, CA 91125, USA. acr@astro.caltech.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15472038" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Dynamic chemical equilibrium in a polar desert pond: a sensitive index of meteorological cycles (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-20
    Description: The dramatic variation in the composition of a brine pond in Antarctica is a seasonal phenomenon. The phase relations of salts in solution are such that hydrologic conditions and temperature determine composition during the austral summer. Temperature is the primary determinant of composition during the winter.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Harris, H J -- Cartwright, K -- Torii, T -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):301-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17800358" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells (2020)
    Springer Nature
    Details
    Publication Date: 2020
    Print ISSN: 1529-2908
    Electronic ISSN: 1529-2916
    Topics: Biology , Medicine
    Published by Springer Nature
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  • 5
    Electronic Resource
    Electronic Resource
    Nonlinear hybrid Boltzmann–particle-in-cell acceleration algorithm (2000)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 7 (2000), S. 3252-3264 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Kinetic simulation of plasmas in which equilibrium occurs over ion time scales poses a computational challenge due to disparity with electron time scales. Hybrid electrostatic particle-in-cell (PIC) algorithms are presented in which most of the electrons reach thermodynamic equilibrium [Maxwell–Boltzmann (MB) distribution function] each time step. Conservation of charge enables convergence of the nonlinear Poisson equation. Energy conservation is used to determine the temperature of the Boltzmann species. This article first develops an algorithm where all the electrons have a MB energy distribution, either with a full MB distribution or with a truncation of the high energy tail. Second, high energy PIC electrons are added to the truncated distribution so that high energy electrons are modeled kinetically by PIC and low energy electrons (the majority) are modeled by the MB distribution. Collisions for PIC electrons are included via a Monte Carlo model, while for the MB electrons, the distributions are integrated with energy dependent cross sections. The MB model is not constrained by the electron time scale which decreases the required computer time by about the square root of the mass ratio of ion to electron. However, the hybrid boundary conditions are more complex and the simulation is not quite self-consistent. Comparison between full PIC and the PIC–MB hybrid is made for simulations of photo-ionized sustained discharges and current-driven dc discharges. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.874191
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  • 6
    Electronic Resource
    Electronic Resource
    Surface wave enhanced collisionless transport in a bounded crossed-field non-neutral plasma : The 41st annual meeting of the division of plasma physics of the american physical society (2000)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 7 (2000), S. 1740-1745 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Electron transport across the magnetic field in a cutoff planar smooth-bore diode is described on the basis of surface waves perpendicular to the magnetic field and along the cathode. A self-consistent (two spatial dimensions and three velocity components) electrostatic particle-in-cell (PIC) simulation of a crossed-field diode produces a near-Brillouin flow which slowly expands across the diode, punctuated by sudden transport across the diode. The theory of slow transport across the diode is explained by the addition of perturbed orbits to the Brillouin shear flow motion of the plasma in the diode. The wave results from the sheared flow instability, so that a definite mechanism behind the surface waves is established. The growth and wavelength of this wave are compared to PIC simulations. A slow drift compared to the shear flow is described which results from an electrostatic ponderomotive-like force in a dc external magnetic field. The slow drift obtained from single particle motion compares well to the expansion of the hub in PIC simulations. The slow expansion of the Brillouin hub leads to configurations that are not stable and quickly decay via a large transport of charge to the anode. Both the slow transport of electrons and current spikes have been observed in experiments. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.873993
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  • 7
    Electronic Resource
    Electronic Resource
    REPLY TO the preceding Discussion by John Logan of “Use of Geophysical Logs to Estimate Water Quality of Basal Pennsylvanian Sandstone, Southwestern Illinois” (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 28 (1990), S. 0 
    Details
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6584.1990.tb02242.x
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  • 8
    Electronic Resource
    Electronic Resource
    Use of Geophysical Logs to Estimate Water Quality of Basal Pennsylvanian Sandstones, Southwestern Illinois (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 27 (1989), S. 0 
    Details
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: Fresh water is found at depths up to 1000 feet in basal Pennsylvanian sandstone aquifers along the southern margin of the Illinois Basin. These aquifers, though not highly productive, represent a significant potential source of ground water in a region of very limited ground-water supplies. A pilot study was undertaken in southwestern Illinois using geophysical logs and limited hydrologic data to evaluate the potential of these aquifers. Water quality, porosity, and permeability were estimated from the geophysical logs; these data were then used in conjunction with data from aquifer performance tests to delineate zones of potable water. The data indicate that fresh-water lenses extend basinward in sandstone paleochannels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6584.1989.tb00482.x
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  • 9
    Electronic Resource
    Electronic Resource
    Infiltration and Hydraulic Conductivity of a Compacted Earthen Liner (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 27 (1989), S. 0 
    Details
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: Infiltration through a small (3 × 9 × 1 m) experimental earthen liner, similar to those used for waste disposal was evaluated. The liner was constructed using full-size compaction equipment, and in-situ ponded infiltration rates were measured using two large (1·5-m diameter) sealed double-ring infiltrometers. An average apparent steady-flux density of 1·5 × 10−7 cm/s was achieved after two to three weeks. Wetting front depths of 7·3 cm and 9·6 cm after 46 days were calculated assuming a Green-Ampt piston flow infiltration system. One of the infiltrometers was ponded with water containing rhodamine dye and after the 46-day infiltration test, a uniform rhodamine dye front was observed at about the 4-cm depth. Sharpness of the dye front suggests that the piston flow assumption is a reasonable one. Apparent saturated hydraulic conductivity of the liner was estimated from the infiltration data to be no more than 3·6 × 10−8 cm/s, meeting the present EPA permeability requirement for earthen liners of no more than 1 × 10−7 cm/s. Transit time for the wetting front to reach the liner bottom at the 0·91-m depth was predicted to be about three years. Seepage flux after liner saturation was estimated at 4·8 × 10−8 cm/s for a liner ponded with 30 cm of water.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6584.1989.tb00002.x
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  • 10
    Electronic Resource
    Electronic Resource
    Scanning tunneling microscope as a high sensitivity radiation detector (1992)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 63 (1992), S. 2099-2100 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We present measurements on the effect of laser radiation impinging on the tunneling gap of a scanning tunneling microscope, causing a modulation of the tunneling gap. We have measured variations in the tunneling current equivalent to microscopic expansions that are as small as 0.03 A(ring), of the order of vibration of individual molecules. The process has also been used for recording the absorption spectrum of an alexandrite crystal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1143174
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