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  • 1
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    Cold and ultracold dynamics of the barrierless D+ + H2 reaction: Quantum reactive calculations for ∼R−4 long range interaction potentials (2015)
    American Institute of Physics (AIP)
    Details
    Publication Date: 2015-11-25
    Description: Quantum reactive and elastic cross sections and rate coefficients have been calculated for D + + H 2 ( v = 0, j = 0) collisions in the energy range from 10 −8 K (deep ultracold regime), where only one partial wave is open, to 150 K (Langevin regime) where many of them contribute. In systems involving ions, the ∼ R −4 behavior extends the interaction up to extremely long distances, requiring a special treatment. To this purpose, we have used a modified version of the hyperspherical quantum reactive scattering method, which allows the propagations up to distances of 10 5  a 0 needed to converge the elastic cross sections. Interpolation procedures are also proposed which may reduce the cost of exact dynamical calculations at such low energies. Calculations have been carried out on the PES by Velilla et al. [J. Chem. Phys. 129 , 084307 (2008)] which accurately reproduces the long range interactions. Results on its prequel, the PES by Aguado et al. [J. Chem. Phys. 112 , 1240 (2000)], are also shown in order to emphasize the significance of the inclusion of the long range interactions. The calculated reaction rate coefficient changes less than one order of magnitude in a collision energy range of ten orders of magnitude, and it is found in very good agreement with the available experimental data in the region where they exist (10-100 K). State-to-state reaction probabilities are also provided which show that for each partial wave, the distribution of HD final states remains essentially constant below 1 K.
    Print ISSN: 0021-9606
    Electronic ISSN: 1089-7690
    Topics: Chemistry and Pharmacology , Physics
    Published by American Institute of Physics (AIP)
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  • 2
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    Beyond universality: Parametrizing ultracold complex-mediated reactions using statistical assumptions (2015)
    American Physical Society (APS)
    Details
    Publication Date: 2015-03-31
    Description: Author(s): Manuel Lara, P. G. Jambrina, J.-M. Launay, and F. J. Aoiz We have calculated accurate quantum reactive and elastic cross sections for the prototypical barrierless reaction D + +H 2 (v=0, j=0) using a modified hyperspherical scattering method. The considered kinetic energy ranges from the ultracold to the Langevin regimes. A reaction rate coefficient practicall... [Phys. Rev. A 91, 030701] Published Mon Mar 30, 2015
    Keywords: Atomic and molecular collisions and interactions
    Print ISSN: 1050-2947
    Electronic ISSN: 1094-1622
    Topics: Physics
    Published by American Physical Society (APS)
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  • 3
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    Signal transduction through prion protein (2000)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2000-09-16
    Description: The cellular prion protein PrPc is a glycosylphosphatidylinositol-anchored cell-surface protein whose biological function is unclear. We used the murine 1C11 neuronal differentiation model to search for PrPc-dependent signal transduction through antibody-mediated cross-linking. A caveolin-1-dependent coupling of PrPc to the tyrosine kinase Fyn was observed. Clathrin might also contribute to this coupling. The ability of the 1C11 cell line to trigger PrPc-dependent Fyn activation was restricted to its fully differentiated serotonergic or noradrenergic progenies. Moreover, the signaling activity of PrPc occurred mainly at neurites. Thus, PrPc may be a signal transduction protein.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mouillet-Richard, S -- Ermonval, M -- Chebassier, C -- Laplanche, J L -- Lehmann, S -- Launay, J M -- Kellermann, O -- New York, N.Y. -- Science. 2000 Sep 15;289(5486):1925-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Differenciation Cellulaire, CNRS-Institut Pasteur, 75724 Paris Cedex 15, France. srichard@pasteur.fr〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10988071" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Caveolin 1 ; *Caveolins ; Cell Compartmentation ; Cell Differentiation ; Enzyme Activation ; Membrane Proteins/metabolism ; Mice ; Neurons/cytology/metabolism ; PrPC Proteins/*metabolism ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins c-fyn ; *Signal Transduction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Influence of the energy-band structure on ultracold reactive processes in lattices (2016)
    American Physical Society (APS)
    Details
    Publication Date: 2016-03-05
    Description: Author(s): H. Terrier, J.-M. Launay, and A. Simoni We study theoretically ultracold collisions in quasi-one-dimensional optical traps for bosonic and fermionic reactive molecules in the presence of a periodic potential along the trap axis. Elastic, reactive, and umklapp processes due to nonconservation of the center-of-mass motion are investigated f… [Phys. Rev. A 93, 032703] Published Fri Mar 04, 2016
    Keywords: Atomic and molecular collisions and interactions
    Print ISSN: 1050-2947
    Electronic ISSN: 1094-1622
    Topics: Physics
    Published by American Physical Society (APS)
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  • 5
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    miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants (2010)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2010-09-18
    Description: The serotonin transporter (SERT) ensures the recapture of serotonin and is the pharmacological target of selective serotonin reuptake inhibitor (SSRI) antidepressants. We show that SERT is a target of microRNA-16 (miR-16). miR-16 is expressed at higher levels in noradrenergic than in serotonergic cells; its reduction in noradrenergic neurons causes de novo SERT expression. In mice, chronic treatment with the SSRI fluoxetine (Prozac) increases miR-16 levels in serotonergic raphe nuclei, which reduces SERT expression. Further, raphe exposed to fluoxetine release the neurotrophic factor S100beta, which acts on noradrenergic cells of the locus coeruleus. By decreasing miR-16, S100beta turns on the expression of serotonergic functions in noradrenergic neurons. Based on pharmacological and behavioral data, we propose that miR-16 contributes to the therapeutic action of SSRI antidepressants in monoaminergic neurons.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Baudry, Anne -- Mouillet-Richard, Sophie -- Schneider, Benoit -- Launay, Jean-Marie -- Kellermann, Odile -- New York, N.Y. -- Science. 2010 Sep 17;329(5998):1537-41. doi: 10.1126/science.1193692.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Cellules Souches, Signalisation et Prions, INSERM U747, Universite Paris Descartes, 75006 Paris, France.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20847275" target="_blank"〉PubMed〈/a〉
    Keywords: 3' Untranslated Regions ; Animals ; Antidepressive Agents, Second-Generation/administration & ; dosage/metabolism/*pharmacology ; Cell Line ; Depression ; Fluoxetine/administration & dosage/metabolism/*pharmacology ; HeLa Cells ; Humans ; Locus Coeruleus/metabolism ; Mice ; MicroRNAs/administration & dosage/genetics/*metabolism ; Nerve Growth Factors/metabolism ; Neurons/drug effects/*metabolism ; Norepinephrine/metabolism ; Protein Biosynthesis ; Raphe Nuclei/drug effects/*metabolism ; S100 Calcium Binding Protein beta Subunit ; S100 Proteins/metabolism ; Serotonin/metabolism ; Serotonin Plasma Membrane Transport Proteins/*genetics/metabolism ; Serotonin Uptake Inhibitors/administration & dosage/metabolism/*pharmacology ; Up-Regulation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Pathogenic prions deviate PrPC signaling in neuronal cells and impair A-beta clearance (2013)
    Springer Nature
    Details
    Publication Date: 2013-01-11
    Description: Pathogenic prions deviate PrPC signaling in neuronal cells and impair A-beta clearance Cell Death and Disease 4, e456 (January 2013). doi:10.1038/cddis.2012.195 Authors: E Pradines, J Hernandez-Rapp, A Villa-Diaz, C Dakowski, H Ardila-Osorio, S Haik, B Schneider, J-M Launay, O Kellermann, J-M Torres & S Mouillet-Richard
    Keywords: prion infectionA-betasignal transductionMMP-9
    Electronic ISSN: 2041-4889
    Topics: Biology , Medicine
    Published by Springer Nature
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  • 7
    Electronic Resource
    Electronic Resource
    A study of the C(1D)+H2→CH+H reaction: Global potential energy surface and quantum dynamics (2001)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 115 (2001), S. 10701-10708 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The adiabatic global potential energy surface of the CH2 system for the first singlet state of A′ symmetry (a˜ 1A′) has been computed. Ab initio, multireference, single and double configuration interaction calculations have been used to characterize this state. This potential energy surface has a calculated well depth of 99.7 kcal/mol relative to the C(1D)+H2 asymptote. The surface has no barrier for the perpendicular C2v geometry, but presents a large barrier (12.35 kcal/mol) for the collinear C∞v geometry. The ab initio calculations were carried out over 1748 geometries and the resulting energies were fitted to a many body expansion. Based on this surface, we have performed the first quantum reactive scattering calculations for the C(1D)+H2(X 1Σg+)→CH(X 2Π)+H(2S) reaction and total angular momentum J=0. The hyperspherical coordinates time-independent method has been used. We note that the state-to-state reaction probabilities as a function of the collision energy show a dense resonance structure which is unusual for this type of atom+diatom reaction. We present also rotational distributions. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1417501
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  • 8
    Electronic Resource
    Electronic Resource
    Damaging effects of Clostridium perfringens delta toxin on blood platelets and their relevance to ganglioside G"M"2
    Amsterdam : Elsevier
    Archives of Biochemistry and Biophysics 262 (1988), S. 59-66 
    Details
    ISSN: 0003-9861
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0003-9861(88)90168-3
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  • 9
    Electronic Resource
    Electronic Resource
    Biochemical and ultrastructural study of the disruption of blood platelets by streptolysin O
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 556 (1979), S. 278-291 
    Details
    ISSN: 0005-2736
    Keywords: (Platelet) ; Cytolysin ; Dense Body ; Streptolysin O ; Ultrastructure
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2736(79)90048-8
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  • 10
    Electronic Resource
    Electronic Resource
    Characterization of estrone sulfatase activity in human thrombocytes
    Amsterdam : Elsevier
    The @Journal of Steroid Biochemistry and Molecular Biology 46 (1993), S. 215-226 
    Details
    ISSN: 0960-0760
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0960-0760(93)90297-A
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