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  • 1
    Publication Date: 2001-09-15
    Description: Throughout the past four decades, silicon semiconductor technology has advanced at exponential rates in both performance and productivity. Concerns have been raised, however, that the limits of silicon technology may soon be reached. Analysis of fundamental, material, device, circuit, and system limits reveals that silicon technology has an enormous remaining potential to achieve terascale integration (TSI) of more than 1 trillion transistors per chip. Such massive-scale integration is feasible assuming the development and economical mass production of double-gate metal-oxide-semiconductor field effect transistors with gate oxide thickness of about 1 nanometer, silicon channel thickness of about 3 nanometers, and channel length of about 10 nanometers. The development of interconnecting wires for these transistors presents a major challenge to the achievement of nanoelectronics for TSI.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meindl, J D -- Chen, Q -- Davis, J A -- New York, N.Y. -- Science. 2001 Sep 14;293(5537):2044-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉School of Electrical and Computer Engineering, Microelectronics Research Center, Georgia Institute of Technology, Atlanta, GA 30332-0269, USA. james.meindl@mirc.gatech.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11557881" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1980-10-17
    Description: Innovative applications of microelectronics in new biomedical implantable instruments offer a singular opportunity for advances in medical research and practice because of two salient factors: (i) beyond all other types of biomedical instruments, implants exploit fully the inherent technical advantages--complex functional capability, high reliability, lower power drain, small size and weight-of microelectronics, and (ii) implants bring microelectronics into intimate association with biological systems. The combination of these two factors enables otherwise impossible new experiments to be conducted and new paostheses developed that will improve the quality of human life.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meindl, J D -- New York, N.Y. -- Science. 1980 Oct 17;210(4467):263-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7423185" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Blood Flow Velocity ; Humans ; Microcomputers ; Monitoring, Physiologic/*instrumentation ; Pacemaker, Artificial/instrumentation ; Prostheses and Implants/*instrumentation ; Rheology ; Telemetry/instrumentation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1982-02-12
    Description: Microelectronics and computers are in use in virtually every aspect of modern medicine. Computers are used widely in medical research, where an important need is for better microelectronic sensors for data acquisition. In medical practice, data collection from patients as well as subsequent storage, retrieval, and manipulation of data are enhanced by the computer. In medical decision-making computers improve accuracy, increase cost-efficiency, and advance understanding of the structure of medical knowledge and of the decision-making process itself. Powerful new noninvasive diagnostic instruments including x-ray tomographic scanners and ultrasonic imaging systems are based on computers. The efficiency and scope of clinical laboratory procedures and advanced analytical instruments are greatly increased by computerization, and careful application of computers has improved the interpretation of diagnostic tests, such as the electrocardiogram, and monitoring of critically ill patients. The powerful sensory, computational, memory, and display capabilities of microcomputer systems and their compact size offer new opportunities to relieve functional deficiencies associated with loss of limbs, paralysis, speech impediments, deafness, and blindness.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meindl, J D -- New York, N.Y. -- Science. 1982 Feb 12;215(4534):792-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7036345" target="_blank"〉PubMed〈/a〉
    Keywords: Clinical Laboratory Techniques ; *Computers ; Critical Care ; Decision Making ; Diagnosis, Computer-Assisted ; *Electronics ; Humans ; Medical History Taking ; Medical Records ; Monitoring, Physiologic ; Prostheses and Implants ; Research ; Sensory Aids ; Tomography, X-Ray Computed ; Ultrasonography
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 18 (1984), S. 797-807 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Implantable biomedical sensors built on a silicon substrate capped with glass are currently being developed for intravascular applications. Electrical techniques for inhibiting thrombus formation on the surface of a proposed optical sensor in direct contact with blood have been investigated. Glass-on-silicon specimens (4 × 1.2 × 0.4 mm3) were coated with indium-tin oxide, a transparent conductor, and implanted in the vena cava and iliac veins of three dogs for 10, 20, or 33 days. The equilibrium surface - blood interface potentials of the specimens were modified by implanted current sources which supplied either direct current (8-15 m̈A) or 100 KHz alternating current (5 m̈A, root mean square). Light-microscopic and scanning electron-microscopic analyses showed each of the DC-polarized specimens to be free of thrombus, in contrast to nonpolarized (control) specimens on which varying amounts of adsorbed protein and thrombus deposits were found. Like the control specimens, the AC-polarized specimens formed thrombus, but the appearance of the deposits differed. These findings support the view that the polarity, magnitude and time dependence of the potential across conducting surface - blood interface significantly influence thrombogenicity. Further work is necessary to determine the roles of electrochemical and electrostatic factors in preventing thrombus formation on foreign materials.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Publication Date: 1979-09-15
    Print ISSN: 0003-6951
    Electronic ISSN: 1077-3118
    Topics: Physics
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  • 6
    Publication Date: 1979-10-01
    Print ISSN: 0003-6951
    Electronic ISSN: 1077-3118
    Topics: Physics
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  • 7
    Publication Date: 2019-01-25
    Description: Doppler ultrasonic blood flowmeters are reviewed in detail. The importance of measurement accuracy for transcutaneous flowmeters and their clinical application is stressed. Doppler imaging was combined with conventional pulse echo imaging, and diagnostic information was extracted from flow signals. The range and extent of applications of Doppler instruments was also presented.
    Keywords: AEROSPACE MEDICINE
    Type: Soc. of Photo-Opt. Instrumentation Engrs. Cardiovascular Imaging and Image Processing; p 53-63
    Format: text
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  • 8
    Publication Date: 2019-07-13
    Description: An extensive evaluation of the practical and theoretical limitations encountered in the use of totally implantable CW Doppler flowmeters is provided. Theoretical analyses, computer models, in-vitro and in-vivo calibration studies describe the sources and magnitudes of potential errors in the measurement of blood flow through the renal artery, as well as larger vessels in the circulatory system. The evaluation of new flowmeter/transducer systems and their use in physiological investigations is reported.
    Keywords: AEROSPACE MEDICINE
    Type: NASA-CR-148131 , SEL-76-004
    Format: application/pdf
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  • 9
    Publication Date: 2019-07-13
    Description: A transcutaneous system for real-time imaging of arteries is described. A transducer probe containing three linear arrays of elements scans tissues within the element Fresnel zones. Each element is multiplexed in turn to a pulsed Doppler processor to permit real-time visualizations of moving targets. Applications of the motion-indicating B-scans are discussed, with special attention to problems in transcutaneous measurement of blood flow.
    Keywords: INSTRUMENTATION AND PHOTOGRAPHY
    Type: Ultrasonics Symposium; Nov 05, 1973 - Nov 07, 1973; Monterey, CA
    Format: text
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  • 10
    Publication Date: 2019-07-13
    Keywords: MAN/SYSTEM TECHNOLOGY AND LIFE SUPPORT
    Type: International Symposium on Acoustical Holography and Imaging; Feb 04, 1975 - Feb 07, 1975; San Diego, CA
    Format: text
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