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  • 1
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    Single-Mode Photonic Band Gap Guidance of Light in Air (1999)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1999-09-08
    Description: The confinement of light within a hollow core (a large air hole) in a silica-air photonic crystal fiber is demonstrated. Only certain wavelength bands are confined and guided down the fiber, each band corresponding to the presence of a full two-dimensional band gap in the photonic crystal cladding. Single-mode vacuum waveguides have a multitude of potential applications from ultrahigh-power transmission to the guiding of cold atoms.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cregan -- Mangan -- Knight -- Birks -- Russell -- Roberts -- Allan -- New York, N.Y. -- Science. 1999 Sep 3;285(5433):1537-1539.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Optoelectronics Group, University of Bath, Claverton Down, Bath BA2 7AY, UK. Defence Evaluation and Research Agency Malvern, St. Andrews Road, Malvern, Worcs WR14 7HR, UK. Corning Incorporated, Corning, New York 14831, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10477511" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Soliton self-frequency shift cancellation in photonic crystal fibers (2003)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2003-09-23
    Description: We report the cancellation of the soliton self-frequency shift in a silica-core photonic crystal fiber with a negative dispersion slope. Numerical and experimental results show that stabilization of the soliton wavelength is accompanied by exponential amplification of the red-shifted Cherenkov radiation emitted by the soliton. The spectral recoil from the radiation acts on the soliton to compensate for the Raman frequency shift. This phenomenon may find applications in the development of a family of optical parametric amplifiers.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Skryabin, D V -- Luan, F -- Knight, J C -- Russell, P St J -- New York, N.Y. -- Science. 2003 Sep 19;301(5640):1705-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physics, University of Bath, Bath BA2 7AY, UK. d.v.skryabin@bath.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/14500977" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Photonic band gap guidance in optical fibers (1998)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1998-11-20
    Description: A fundamentally different type of optical waveguide structure is demonstrated, in which light is confined to the vicinity of a low-index region by a two-dimensional photonic band gap crystal. The waveguide consists of an extra air hole in an otherwise regular honeycomb pattern of holes running down the length of a fine silica glass fiber. Optical fibers based on this waveguide mechanism support guided modes with extraordinary properties.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Knight -- Broeng -- Birks -- Russell -- New York, N.Y. -- Science. 1998 Nov 20;282(5393):1476-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Optoelectronics Group, Department of Physics, University of Bath, Claverton Down, Bath BA2 7AY, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9822375" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Applied optics. New ways to guide light (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-04-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Knight, J C -- Russell, P St J -- New York, N.Y. -- Science. 2002 Apr 12;296(5566):276-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11951025" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Stimulated Raman scattering in hydrogen-filled hollow-core photonic crystal fiber (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-10-12
    Description: We report on stimulated Raman scattering in an approximately 1-meter-long hollow-core photonic crystal fiber filled with hydrogen gas under pressure. Light was guided and confined in the 15-micrometer-diameter hollow core by a two-dimensional photonic bandgap. Using a pulsed laser source (pulse duration, 6 nanoseconds; wavelength, 532 nanometers), the threshold for Stokes (longer wavelength) generation was observed at pulse energies as low as 800 +/- 200 nanojoules, followed by a coherent anti-Stokes (shorter wavelength) generation threshold at 3.4 +/- 0.7 microjoules. The pump-to-Stokes conversion efficiency was 30 +/- 3% at a pulse energy of only 4.5 microjoules. These energies are almost two orders of magnitude lower than any other reported energy, moving gas-based nonlinear optics to previously inaccessible parameter regimes of high intensity and long interaction length.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Benabid, F -- Knight, J C -- Antonopoulos, G -- Russell, P St J -- New York, N.Y. -- Science. 2002 Oct 11;298(5592):399-402.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Optoelectronics Group, Department of Physics, University of Bath, Claverton Down, Bath BA2 7AY, UK. pysab@bath.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12376698" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression (2014)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2014-03-08
    Description: To systematically investigate the impact of immune stimulation upon regulatory variant activity, we exposed primary monocytes from 432 healthy Europeans to interferon-gamma (IFN-gamma) or differing durations of lipopolysaccharide and mapped expression quantitative trait loci (eQTLs). More than half of cis-eQTLs identified, involving hundreds of genes and associated pathways, are detected specifically in stimulated monocytes. Induced innate immune activity reveals multiple master regulatory trans-eQTLs including the major histocompatibility complex (MHC), coding variants altering enzyme and receptor function, an IFN-beta cytokine network showing temporal specificity, and an interferon regulatory factor 2 (IRF2) transcription factor-modulated network. Induced eQTL are significantly enriched for genome-wide association study loci, identifying context-specific associations to putative causal genes including CARD9, ATM, and IRF8. Thus, applying pathophysiologically relevant immune stimuli assists resolution of functional genetic variants.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064786/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064786/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fairfax, Benjamin P -- Humburg, Peter -- Makino, Seiko -- Naranbhai, Vivek -- Wong, Daniel -- Lau, Evelyn -- Jostins, Luke -- Plant, Katharine -- Andrews, Robert -- McGee, Chris -- Knight, Julian C -- 074318/Wellcome Trust/United Kingdom -- 088891/Wellcome Trust/United Kingdom -- 090532/Wellcome Trust/United Kingdom -- 090532/Z/09/Z/Wellcome Trust/United Kingdom -- 281824/European Research Council/International -- 98082/Medical Research Council/United Kingdom -- G1001708/Medical Research Council/United Kingdom -- New York, N.Y. -- Science. 2014 Mar 7;343(6175):1246949. doi: 10.1126/science.1246949.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24604202" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Antigens, CD14/immunology ; Aryl Hydrocarbon Hydroxylases/genetics ; Basic-Leucine Zipper Transcription Factors/genetics ; CARD Signaling Adaptor Proteins/genetics ; Chromosome Mapping ; Crohn Disease/epidemiology/*genetics ; Cytochrome P-450 CYP1B1 ; Female ; Gene Expression Regulation/*immunology ; *Genetic Predisposition to Disease ; Genetic Variation ; Genome-Wide Association Study ; Humans ; Immunity, Innate/*genetics ; Indoleamine-Pyrrole 2,3,-Dioxygenase/genetics ; Interferon Regulatory Factor-2/genetics ; Interferon Regulatory Factors/genetics ; Interferon-gamma/pharmacology ; Male ; Middle Aged ; Monocytes/drug effects/*immunology ; Polymorphism, Single Nucleotide ; Quantitative Trait Loci ; Receptors, Purinergic P2/genetics ; Young Adult
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
    Electronic Resource
    Electronic Resource
    The Structure of the Cactus Sterol Macdougallin (14α-Methyl-[UNK]-Cholestene-3β,6α-Diol)—A Novel Link in Sterol Biogenesis1 (1963)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 85 (1963), S. 835-835 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00889a056
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Compact, stable and efficient all-fibre gas cells using hollow-core photonic crystal fibres (2005)
    [s.l.] : Macmillian Magazines Ltd.
    Nature 434 (2005), S. 488-491 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Gas-phase materials are used in a variety of laser-based applications—for example, in high-precision frequency measurement, quantum optics and nonlinear optics. Their full potential has however not been realized because of the lack of a suitable technology for creating gas cells that ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature03349
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  • 9
    Electronic Resource
    Electronic Resource
    Transformation and control of ultra-short pulses in dispersion-engineered photonic crystal fibres (2003)
    [s.l.] : Macmillian Magazines Ltd.
    Nature 424 (2003), S. 511-515 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Photonic crystal fibres (PCFs) offer greatly enhanced design freedom compared to standard optical fibres. For example, they allow precise control of the chromatic dispersion (CD) profile—the frequency dependence of propagation speed—over a broad wavelength range. This permits studies of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature01798
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  • 10
    Electronic Resource
    Electronic Resource
    Near-field optical microscopy of thin photonic crystal films (1999)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 85 (1999), S. 6337-6342 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Near-field optical microscopy is used to image the light propagating in a Si3N4-on-silica film with a strip of deeply etched submicron holes in the center. Fringe patterns created by interference between incident and diffracted guided modes are observed in the smooth waveguide surrounding the large air-hole photonic film. Observation of the fields in the photonic crystal regions indicates that out-of-plane scattering at the smooth/periodic transitions and leakage caused by grating coupling play major roles. The effects of different air-hole sizes and lattice pitches are also explored. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.370135
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