ISSN:
1420-9071
Keywords:
Taxoid
;
taxuspine D
;
yew
;
Taxus cuspidata
;
microtubule depolymerization
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract A new taxane diterpenoid, taxuspine D (1), possessing an enolacetate moiety, has been isolated from stems of the Japanese yewTaxus cuspidata Sieb. et Zucc., and the structure elucidated on the basis of spectroscopic data. Taxuspine D (1) markedly inhibited Ca2+-induced depolymerization of microtubules.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02128750
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