ISSN:
1573-8221
Keywords:
gangliosides
;
phagocytes
;
oxidative burst
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract It is shown that ganglioside GM1 in picomolar concentrations stimulates the phorbol-12-myristate-13-acetate (PMA)-induced generation of active forms of oxygen by neutrophils and peritoneal macrophages. GM1 (10−11 M) is found to enhance the luminol-dependent chemiluminescence induced by 10−8 M PMA in mouse macrophages in comparison with the effect of PMA alone.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02444077
Permalink