Publication Date:
2014-06-29
Description:
Article SUMO forms flexible polymeric chains that can interact with ubiquitin ligases, such as RNF4. Here Xu et al . have used NMR spectroscopy and biochemical experiments to investigate the interaction between SUMO and RNF4, and propose a mechanism for delivery of substrates to the ubiquitination machinery. Nature Communications doi: 10.1038/ncomms5217 Authors: Yingqi Xu, Anna Plechanovová, Peter Simpson, Jan Marchant, Orsolya Leidecker, Sebastian Kraatz, Ronald T. Hay, Steve J. Matthews
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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