ISSN:
0265-9247
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Medicine
Notes:
Our defence against microbes depends largely on the ability of neutrophils to migrate from the blood stream to sites of infection. Although the ability of animal cells to move may be primitive, and also fundamental for a number of phenomena in biology, the cellular mechanism by which neutrophils are able to move rapidly towards the infection remains an enigma. Even though the structures of the receptors involved have been sequenced and many of the molecules involved in neutrophil adherence and traction identified, the essential mechanisms that control and regulate the neutrophil motor remain obscure. Here, an outline of the fundamental inadequacies in our current understanding is given, along with some recent developments that promise to produce some significant advances.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bies.950190712
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