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  • 1
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    Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-10-05
    Description: Comparison of the genomes and proteomes of the two diptera Anopheles gambiae and Drosophila melanogaster, which diverged about 250 million years ago, reveals considerable similarities. However, numerous differences are also observed; some of these must reflect the selection and subsequent adaptation associated with different ecologies and life strategies. Almost half of the genes in both genomes are interpreted as orthologs and show an average sequence identity of about 56%, which is slightly lower than that observed between the orthologs of the pufferfish and human (diverged about 450 million years ago). This indicates that these two insects diverged considerably faster than vertebrates. Aligned sequences reveal that orthologous genes have retained only half of their intron/exon structure, indicating that intron gains or losses have occurred at a rate of about one per gene per 125 million years. Chromosomal arms exhibit significant remnants of homology between the two species, although only 34% of the genes colocalize in small "microsyntenic" clusters, and major interarm transfers as well as intra-arm shuffling of gene order are detected.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zdobnov, Evgeny M -- von Mering, Christian -- Letunic, Ivica -- Torrents, David -- Suyama, Mikita -- Copley, Richard R -- Christophides, George K -- Thomasova, Dana -- Holt, Robert A -- Subramanian, G Mani -- Mueller, Hans-Michael -- Dimopoulos, George -- Law, John H -- Wells, Michael A -- Birney, Ewan -- Charlab, Rosane -- Halpern, Aaron L -- Kokoza, Elena -- Kraft, Cheryl L -- Lai, Zhongwu -- Lewis, Suzanna -- Louis, Christos -- Barillas-Mury, Carolina -- Nusskern, Deborah -- Rubin, Gerald M -- Salzberg, Steven L -- Sutton, Granger G -- Topalis, Pantelis -- Wides, Ron -- Wincker, Patrick -- Yandell, Mark -- Collins, Frank H -- Ribeiro, Jose -- Gelbart, William M -- Kafatos, Fotis C -- Bork, Peer -- New York, N.Y. -- Science. 2002 Oct 4;298(5591):149-59.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12364792" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anopheles/chemistry/*genetics/physiology ; Biological Evolution ; Chromosome Inversion ; Chromosomes/genetics ; Cluster Analysis ; Dosage Compensation, Genetic ; Drosophila Proteins/chemistry/genetics/physiology ; Drosophila melanogaster/chemistry/*genetics/physiology ; Exons ; Gene Order ; Genes, Insect ; *Genome ; Insect Proteins/chemistry/genetics/physiology ; Introns ; Physical Chromosome Mapping ; Protein Structure, Tertiary ; *Proteome ; Pseudogenes ; Sequence Homology, Nucleic Acid ; Species Specificity ; Synteny
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Textpresso Central: a customizable platform for searching, text mining, viewing, and curating biomedical literature (2018)
    BioMed Central
    Details
    Publication Date: 2018-03-12
    Description: The biomedical literature continues to grow at a rapid pace, making the challenge of knowledge retrieval and extraction ever greater. Tools that provide a means to search and mine the full text of literature t...
    Electronic ISSN: 1471-2105
    Topics: Biology , Computer Science
    Published by BioMed Central
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  • 3
    Electronic Resource
    Electronic Resource
    Experimental and numerical studies of shock wave focusing in water (1988)
    Springer
    Experiments in fluids 6 (1988), S. 209-216 
    Details
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The focusing of plane shock waves and spherical blast waves in water by parabolic and ellipsoidal reflectors is studied experimentally and numerically. The numerical computations are performed by a second order method based on an extension of Godunov's method, which is called piecewise-linear method. Tests of this method and a comparison with pressure measurements show a strong dependence of the maximum pressure attained in the focal region on the mesh size. Outside this focal region, however, good agreement between the pressure measurements and the result of the numerical computation is found. Furthermore it is shown by numerical computation, that non-linear effects in the focusing process may be partly avoided by an optimized reflector contour which depends on the strength of the incident shock wave. This modification provides that the maximum pressure is attained at the geometric focus and not at a location between reflector surface and geometrical focus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00230733
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  • 4
    Electronic Resource
    Electronic Resource
    Oxalate accumulation from citrate by Aspergillus niger (1975)
    Springer
    Archives of microbiology 104 (1975), S. 159-162 
    Details
    ISSN: 1432-072X
    Keywords: Oxalate Accumulation ; Aspergillus ; Citrate Degradation ; Tricarboxylic Acid Cycle ; Enzyme Synthesis ; Fluoroacetate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Carbon-14 was incorporated into oxalate and CO2 from either citrate-1,5-14C, succinate-1,4-14C, or fumarate-1,4-14C by cultures of Aspergillus niger pregrown on a medium which contained glucose as the sole carbon source and which did not allow citrate accumulation. In cell-free extracts of mycelium forming oxalate and CO2 from added citrate the following enzymes of the tricarboxylic acid (TCA) cycle were identified: citrate synthase (CE 4.1.3.7), aconitate hydratase (EC 4.2.1.3), NAD- and NADP-dependent isocitrate dehydrogenase (EC 1.1.1.41, 1.1.1.42), (α-oxoglutarate dehydrogenase (EC 1.2.4.2), succinate dehydrogenase (EC1.3.99.1), fumarate hydratase (EC 4.2.1.2), and malate dehydrogenase (EC 1.1.1.37). The in vitro activity of aconitate hydratase and of NADP-dependent isocitrate dehydrogenase was shown to be almost identical to the rate of in vivo degradation of citrate or to exceed this rate. The degradation of citrate to oxalate was inhibited completely by 9 mM fluoroacetate. It is concluded that the TCA cycle is involved in the formation of oxalate from citrate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00447318
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  • 5
    Electronic Resource
    Electronic Resource
    The responses of central octavolateralis cells to moving sources (1996)
    Springer
    Journal of comparative physiology 179 (1996), S. 455-471 
    Details
    ISSN: 1432-1351
    Keywords: Lateral line ; Teleost fish ; Catfish ; Mechanoreception
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Mechanosensory lateral line units recorded from the medulla (medial octavolateralis nucleus) and midbrain (torus semicircularis) of the bottom dwelling catfish Ancistrus sp. responded to water movements caused by an object that passed the fish laterally. In terms of peak spike rate or total number of spikes elicited responses increased with object speed and sometimes showed saturation (Figs. 7, 14). At sequentially greater distances the responses of most medullary lateral line units decayed with object distance (Fig. 11). Units tuned to a certain object speed or distance were not found. The signed directionality index of most lateral line units was between −50 and +50, i.e. these units were not or only slightly sensitive to the direction of object motion (Figs. 10, 17). However, some units were highly directionally sensitive in that the main features of the response histograms and/or peak spike rates clearly depended on the direction of object movement (e.g. Fig. 9C, D and Fig. 16). Midbrain lateral line units of Ancistrus may receive input from more than one sensory modality. All bimodal lateral line units were OR units, i.e., the units were reliably driven by a unimodal stimulus of either modality. Units which receive bimodal input may show an extended speed range (e.g. Fig. 18).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00192313
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  • 6
    Electronic Resource
    Electronic Resource
    „Fouling“-Vorgänge bei der Verdampfung von Argon im waagerecht durchströmten Rohr (1982)
    Springer
    Heat and mass transfer 17 (1982), S. 47-53 
    Details
    ISSN: 1432-1181
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Description / Table of Contents: Zusammenfassung Bei Messungen des Wärmeübergangs beim Strömungssieden von Argon wurde ein zeitlicher Anstieg der Wandtemperatur beobachtet, während die Einstellparameter Wärmestromdichte, Massenstromdichte, Dampfgehalt und Systemdruck konstant blieben. Dieser Temperaturanstieg endete nach mehreren Stunden bei einer beträchtlich höheren Wandtemperatur oder mit dem Eintreten der Siedekrise. Als Ursache für dieses Phänomen wurde die Ablagerung von im Argon gelöstem CO2 an der Heizfläche ermittelt, wobei zu beachten ist, daß die Reinheit des verwendeten Argons größer als 99,996 vol-% war. In weiteren Versuchen wurde der Einfluß der CO2-Konzentration auf diesen Fouling-Vorgang bestimmt und ein Verfahren entwickelt, um das CO2 aus dem Meßkreislauf zu entfernen. Der Ablagerungsmechanimus und der Einfluß der Betriebsparameter auf die Ablagerungsgeschwindigkeit können mit Modellvorstellungen zur Blasenbildung erklärt werden.
    Notes: Abstract During heat transfer measurements at flow boiling of argon a transient increase of the wall temperature has been observed, though the parameters such as heat flux, mass velocity, flow quality and system pressure were kept constant. This temperature drifting ended after several hours at a considerably higher wall temperature or with the boiling crisis. Although the purity of the test substance was higher than 99.996 vol-%, this phenomenon was caused by the solidification of CO2 on the heating surface. Further investigations showed the influence of the CO2-concentration on the drifting as well as a method to remove the CO2 out of the test fluid. Both, fouling mechanism and influence of the parameters on the fouling, can be explained satisfactorily by means of bubble-growth mechanisms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01686965
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  • 7
    Electronic Resource
    Electronic Resource
    Natural occurrence of Fusarium toxins in barley grown in a southwestern area of Germany (1993)
    Springer
    Bulletin of environmental contamination and toxicology 51 (1993), S. 532-537 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00192168
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  • 8
    Electronic Resource
    Electronic Resource
    Über Veränderungen der stofflichen Zusammensetzung von Scenedesmus obliquus (Turp.) Krüger im Licht-Dunkel-Wechsel (1960)
    Springer
    Naturwissenschaften 47 (1960), S. 453-453 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00639933
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  • 9
    Electronic Resource
    Electronic Resource
    Übersicht über die spätglaziale Vegetationsentwicklung im küstenfernen nordostdeutschen Diluvialgebiet (1965)
    Springer
    Naturwissenschaften 52 (1965), S. 16-17 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00631546
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  • 10
    Electronic Resource
    Electronic Resource
    Pycnonuclear triple-alpha-fusion rate in hypernetted chain Approximation (1992)
    Springer
    The European physical journal 342 (1992), S. 133-140 
    Details
    ISSN: 1434-601X
    Keywords: 21.30 ; 67.20 ; 97.60
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We have studied the helium plasma in the hypernetted-chain-Approximation considering both short-ranged internuclear and long-ranged Coulomb interactions. The optimal two-particle wave function has been determined in HNC/0 approximation. The two-particle distribution functions, which have been calculated in various orders of HNC/n approximations (n=0, 4, 5), are used to determine the pycnonuclear triple-alpha-fusion rate in the density regime 108 g/cm3≤ρ≤1010 g/cm3, in which the fusing of three alpha-particles to form a12C-nucleus plays an important role in the crust evolution of an accreting old neutron star. Our calculation supports the idea that the helium liquid undergoes a phase transition to stable8Be matter at densities slightly lower thanρ≈3×109 g/ cm3 as the plasma induced screening potential then becomes strong enough to bind the8Be ground state.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01288460
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