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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 88 (2000), S. 3166-3169 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: An optically pumped intersubband laser generator is proposed in which the continuum states above an Al0.2Ga0.8As–GaAs–Al0.2Ga0.8As single quantum well with a width of L=17 nm serve as the highest level in a four-level laser system. The design allows much greater flexibility in the choice of pumping source and simplifies considerably the device fabrication. We have obtained the electronic subband structure of the proposed device and utilized a simple rate equation approach to examine the electron density in different states under optical pumping. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 3 (1968), S. 629-634 
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The strengths of various glasses, with a range of expansion coefficients, containing 10 vol % thoria spheres, of diameter 50 to 700μm, have been measured. Stresses occur around the spheres, due to differences in the expansion coefficients of the glass and the spheres, on cooling from the fabrication temperature. Stress magnification occurs near the spheres, due to differences in elastic properties, in the presence of an applied stress. When the expansion coefficient of the sphere is greater than that of the glass, circumferential cracks form around the spheres but only when the sphere diameter is greater than a critical value. An approximate value for the critical diameter may be obtained by an energy balance criterion. Cracks may form around spheres smaller than the critical diameter under application of applied stress at stresses below the macroscopic fracture stress. In these cases the strength is governed by a Griffith relationship with the crack size equal to the sphere diameter. When the expansion coefficients of the spheres and glass are similar, the strength of the glass is reduced only when large spheres (⪞300μm diameter) are present. When the expansion coefficient of the spheres is less than that of the glass, linking radial cracks form between the spheres and the material has very low strength.
    Type of Medium: Electronic Resource
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  • 3
    Publication Date: 2013-06-08
    Description: All orthobunyaviruses possess three genome segments of single-stranded negative sense RNA that are encapsidated with the virus-encoded nucleocapsid (N) protein to form a ribonucleoprotein (RNP) complex, which is uncharacterized at high resolution. We report the crystal structure of both the Bunyamwera virus (BUNV) N–RNA complex and the unbound Schmallenberg virus (SBV) N protein, at resolutions of 3.20 and 2.75 Å, respectively. Both N proteins crystallized as ring-like tetramers and exhibit a high degree of structural similarity despite classification into different orthobunyavirus serogroups. The structures represent a new RNA-binding protein fold. BUNV N possesses a positively charged groove into which RNA is deeply sequestered, with the bases facing away from the solvent. This location is highly inaccessible, implying that RNA polymerization and other critical base pairing events in the virus life cycle require RNP disassembly. Mutational analysis of N protein supports a correlation between structure and function. Comparison between these crystal structures and electron microscopy images of both soluble tetramers and authentic RNPs suggests the N protein does not bind RNA as a repeating monomer; thus, it represents a newly described architecture for bunyavirus RNP assembly, with implications for many other segmented negative-strand RNA viruses.
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
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  • 4
    Publication Date: 2012-05-15
    Description: The recent publication of an updated thermodynamic dataset for petrological calculations provides an opportunity to illustrate the relationship between experimental data and the dataset, in the context of a new set of activity–composition models for several key minerals. These models represent orthopyroxene, clinopyroxene and garnet in the system CaO–MgO–Al 2 O 3 –SiO 2 (CMAS), and are valid up to 50 kbar and at least 1800 °C; they are the first high-temperature models for these phases to be developed for the Holland & Powell dataset. The models are calibrated with reference to phase-relation data in the subsystems CaO–MgO–SiO 2 (CMS) and MgO–Al 2 O 3 –SiO 2 (MAS), and will themselves form the basis of models in larger systems, suitable for calculating phase equilibria in the crust and mantle. In the course of calibrating the models, it was necessary to consider the reaction orthopyroxene + clinopyroxene + spinel = garnet + forsterite in CMAS, representing a univariant transition between simple spinel and garnet lherzolite assemblages. The high-temperature segment of this reaction has been much disputed. We offer a powerful thermodynamic argument relating this reaction to the equivalent reaction in MAS, that forces us to choose between good model fits to the data in MAS or to the more recent data in CMAS. We favour the fit to the MAS data, preserving conformity with a large body of experimental and thermodynamic data that are incorporated as constraints on the activity–composition modelling via the internally consistent thermodynamic dataset.
    Print ISSN: 0263-4929
    Electronic ISSN: 1525-1314
    Topics: Geosciences
    Published by Wiley
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  • 5
    Publication Date: 2012-05-15
    Description: A fully thermodynamic model for mafic melt in CaO–MgO–Al 2 O 3 –SiO 2 (CMAS) has been calibrated, for calculation of melting equilibria in the pressure range 0–50 kbar. It is intended as a preliminary step towards a large-system melt model, suitable for exploring melting, melt loss and crystallization processes in a wide range of natural rock compositions. Calibration was performed with attention to the model's behaviour in its compositional subsystems, as a rigorous test of model structure and parameterization. The model is consistent with the latest Holland & Powell thermodynamic data set, and can therefore be used to calculate phase relations in conjunction with the many solid-phase activity–composition models written for the data set. Model calculations successfully reproduce experimental melting reactions in CMAS spinel lherzolite and garnet lherzolite assemblages, as well as sapphirine- and kyanite-bearing assemblages, at moderate to high pressure. Thermodynamically sensitive features, such as thermal divides are also recovered. However, some changes to the model structure will be required before the model can describe the full range of mafic and ultramafic melt compositions known from experiment at low pressures.
    Print ISSN: 0263-4929
    Electronic ISSN: 1525-1314
    Topics: Geosciences
    Published by Wiley
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  • 6
    Publication Date: 2016-01-09
    Description: The unconventional mRNA capping enzyme (GDP polyribonucleotidyltransferase, PRNTase; block V) domain in RNA polymerase L proteins of non-segmented negative strand (NNS) RNA viruses (e.g. rabies, measles, Ebola) contains five collinear sequence elements, Rx(3)Wx(3–8)xGxx(P/A) (motif A; , hydrophobic; , hydrophilic), (Y/W)GSxT (motif B), W (motif C), HR (motif D) and xxx(F/Y)Qxx (motif E). We performed site-directed mutagenesis of the L protein of vesicular stomatitis virus (VSV, a prototypic NNS RNA virus) to examine participation of these motifs in mRNA capping. Similar to the catalytic residues in motif D, G1100 in motif A, T1157 in motif B, W1188 in motif C, and F1269 and Q1270 in motif E were found to be essential or important for the PRNTase activity in the step of the covalent L-pRNA intermediate formation, but not for the GTPase activity that generates GDP (pRNA acceptor). Cap defective mutations in these residues induced termination of mRNA synthesis at position +40 followed by aberrant stop–start transcription, and abolished virus gene expression in host cells. These results suggest that the conserved motifs constitute the active site of the PRNTase domain and the L-pRNA intermediate formation followed by the cap formation is essential for successful synthesis of full-length mRNAs.
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
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  • 7
    Publication Date: 2016-12-10
    Description: Fisheries managers are increasingly required to develop regulatory frameworks to more effectively manage recreational catches in the marine environment. Although the limitations of conventional controls such as size and bag limits and restricted seasons are recognized, harvest tags that are commonly used to regulate hunting, are rarely applied in marine recreational fisheries. Following overfishing of snapper ( Chrysophrys auratus ) in Shark Bay, Western Australia, a broad range of management reforms were progressively introduced from 1998 onwards to limit recreational catches and assist stock recovery. Since 2003, these included a harvest tag system in Freycinet Estuary whereby a limited number of harvest tags were made available each year via a ballot. The effectiveness of harvest tags in terms of stock rebuilding and acceptance by recreational fishers was evaluated using: annual phone surveys of all harvest tag recipients between 2011 and 2013; analysis of compliance statistics collected between 2004 and 2015; and interviews with experienced compliance officers. The overall costs of administration and compliance were also assessed. The capacity of harvest tags to successfully constrain the total annual recreational catch contributed to the recovery of the snapper stock in Freycinet Estuary to management target levels within a 10–12 year timeframe. The majority of harvest tag recipients interviewed considered harvest tags were effective in the management of snapper; cost per tag was reasonable; and compliance in the fishery was high. High levels of compliance are essential if harvest tags are to provide a robust management tool to limit total catch and a useful reference frame for angler surveys. Harvest tags have considerable potential with other marine recreational fisheries where catch limits are required to rebuild and sustain valuable but vulnerable fish stocks.
    Print ISSN: 1054-3139
    Electronic ISSN: 1095-9289
    Topics: Biology , Geosciences , Physics
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  • 8
    Publication Date: 2014-10-19
    Print ISSN: 1745-2473
    Electronic ISSN: 1745-2481
    Topics: Physics
    Published by Springer Nature
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  • 9
    Publication Date: 2011-09-01
    Print ISSN: 0022-1376
    Electronic ISSN: 1537-5269
    Topics: Geosciences
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  • 10
    Publication Date: 2000-09-15
    Print ISSN: 0021-8979
    Electronic ISSN: 1089-7550
    Topics: Physics
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