ISSN:
1573-2614
Keywords:
Oxygen
;
blood levels
;
hypoxia
;
Blood
;
oxygen tension
;
Blood gas analysis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Computer Science
,
Medicine
Notes:
Abstract To determine whether ureteral urine oxygen tension could serve as a monitor of renal hypoxia and its relationship to other renal O2 tension parameters, we simultaneously measured femoral artery (PaO2), renal vein (Pr $$\bar v$$ O2), renal surface (PrsO2), and ureteral urine (PuO2) oxygen tensions in 8 anesthetized pigs while incrementally decreasing the inspired oxygen concentration (FiO2) from 21% to 12%. Renal artery blood flow, measured by transit time ultrasound, renal oxygen consumption, and thermodilution cardiac output, was constant. Changes in PaO2, Pr $$\bar v$$ O2, PrsO2, and PuO2 caused by decreasing FiO2 were evaluated by one-way analysis of variance. The relationships between PuO2 and the other O2 tension parameters were evaluated by correlation coefficient and linear regression statistics. Of six possible O2 decrements (combinations of 3, 6, and 9%), only Pr $$\bar v$$ O2 significantly decreased with all six decrements. PuO2 decreased when FiO2 decreased 6% or more. PuO2 is not a sensitive indicator of systemic hypoxia. Under constant renal perfusion and oxygen consumption, PuO2 had a correlation coefficient of 0.80 and a regression equation of PuO2=0.84 (Pr $$\bar v$$ O2)+11.6, with Pr $$\bar v$$ O2. PuO2 is related to Pr $$\bar v$$ O2 when renal perfusion is constant.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01627629
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