ISSN:
1573-6857
Keywords:
alternative splicing
;
Drosophila
;
dunce
;
pleiotropy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract The D. melanogaster dunce gene is involved in both the learning and memory processes of the fly. The gene encodes for a cAMP-specific phosphodiesterase, a function playing a central role in the regulation of the intracellular cAMP level. Molecular cloning of dunce has so far not been completely achieved, although it is known that the gene encodes a large set of RNAs and has a complex organization, extending for more than 140 kilobases and containing several genes within its introns. Here wer report the isolation and the characterization of 21/7, a cDNA clone representative of a novel dunce splicing pattern. The nucleotide sequence of this clone led to the identification of a dunce exon included in at least one transcript so far uncharacterized.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00240555
Permalink