Publication Date:
2013-02-27
Description:
In PNAS, Sardi et al. describe that viral vector-mediated increase in glucocerebrosidase enzyme (GCase) activity can reverse synuclein-related pathological features and improve behavioral function in the D409V mouse model of Gaucher disease (GD) (1). This important study has several implications for our understanding of the pathogenesis of Parkinson disease (PD)...
Print ISSN:
0027-8424
Electronic ISSN:
1091-6490
Topics:
Biology
,
Medicine
,
Natural Sciences in General
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