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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Pharmacy world & science 12 (1990), S. 240-242 
    ISSN: 1573-739X
    Keywords: Adsorption ; Drug stability ; Parenteral nutrition ; Somatostatin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The stability of somatostatin, added to a total parenteral nutrition formula, in glass containers and in plastic ethylene vinyl acetate containers was investigated. The somatostatin concentration decreased immediately from 3μg/ml to 0.3–0.6μg/ml after addition to the emulsion. In spite of this rapid decrease, somatostatin concentrations remained stable with values of 0.4–0.7μg/ml during the follow-up period (24 h). These findings could be explained assuming adsorption to the surface of the container.
    Type of Medium: Electronic Resource
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