ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Metabolites from Microorganisms. 160th Communication. Conocandin, a new Fungistatic Antibiotic.From a strain of Hormococcus conorum (SACC. ET ROUM.) ROBACK A 32′287, conocandin, a novel type C18-fatty acid with high and specific in vitro fungistatic activity was isolated by means of counter current distribution and silicagel chromatography. The antibiotic is a viscous oil with the molecular formula C18H30O3. It is characterized by IR. and NMR. spectra, ester derivatives and the products of acid rearrangement and ozonolytic degradation. The structure of (E)-2-methylidene-10-methyl-trans-3,4-epoxy-9-hexadecenoic acid (1) is proposed.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19760590726
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