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  • 1
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    Deleted HTLV-I provirus in blood and cutaneous lesions of patients with mycosis fungoides (1991)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1991-07-19
    Description: Mycosis fungoides, a rare form of cutaneous T cell leukemia/lymphoma, is suspected of having a viral etiology on the basis of certain similarities to adult T cell leukemia, which is associated with human T cell leukemia/lymphoma virus type I (HTLV-I) infection. Cell lines were established from peripheral blood mononuclear cells (PBMC) of an HTLV-I-seronegative patient with mycosis fungoides. DNA hybridization analysis revealed the presence of HTLV-I-related sequences with unusual restriction endonuclease sites. Sequence analysis of subcloned fragments demonstrated the presence of a monoclonally integrated provirus with a 5.5-kilobase deletion involving large regions of gag and env and all of pol. Additional evidence for the presence of deleted proviruses was found by polymerase chain reaction (PCR) amplification of DNA from cutaneous lesions of five other HTLV-I-seronegative patients. The findings suggest that HTLV-I infection may be involved in the etiology of at least certain cases of mycosis fungoides.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hall, W W -- Liu, C R -- Schneewind, O -- Takahashi, H -- Kaplan, M H -- Roupe, G -- Vahlne, A -- CA51012-01A1/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1991 Jul 19;253(5017):317-20.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Infectious Disease, North Shore University Hospital-Cornell University Medical College, Manhasset, NY 11030.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1857968" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; *Chromosome Deletion ; DNA, Neoplasm/genetics/isolation & purification ; DNA, Viral/genetics/isolation & purification ; *Genes, Viral ; Human T-lymphotropic virus 1/genetics/*isolation & purification ; Humans ; Lymphocytes/*microbiology ; Molecular Sequence Data ; Mycosis Fungoides/blood/*microbiology ; Oligonucleotide Probes ; Polymerase Chain Reaction ; Proviruses/genetics/*isolation & purification ; Restriction Mapping ; Sequence Homology, Nucleic Acid ; Skin/*microbiology ; Skin Neoplasms/blood/*microbiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Electrical transcutaneous nerve stimulation for relief of itch (1975)
    Springer
    Details
    Publication Date: 1975-02-01
    Print ISSN: 0014-4754
    Topics: Biology , Medicine
    Published by Springer
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  • 3
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    Cytogenetic studies and in vitro colony growth in patients with mastocytosis (1987)
    American Society of Hematology
    Details
    Publication Date: 1987-12-01
    Description: Cytogenetic analysis of bone marrow cells and in vitro growth for bone marrow granulocytic-macrophage stem cells have been performed in 13 patients with mastocytosis, six with systemic mastocytosis, and seven with urticaria pigmentosa. Clones with chromosome abnormalities were found in five patients. The number of clusters and/or colonies after seven days in culture was increased in seven patients, compared with the growth in a control group. Three patients with chromosome abnormalities showed an abnormal growth pattern, yet exhibited normal peripheral blood values. Two patients with systemic mastocytosis had clones with chromosome abnormalities and some abnormal hematological values. The proportion of patients with chromosome abnormalities and an abnormal growth pattern was higher among these patients with mastocytosis than in healthy control subjects. These results may be of interest when discussing the origin of mast cell disorders and indicate an association with the myeloproliferative disorders.
    Print ISSN: 0006-4971
    Electronic ISSN: 1528-0020
    Topics: Biology , Medicine
    Published by American Society of Hematology
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  • 4
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    Cytogenetic studies and in vitro colony growth in patients with mastocytosis (1987)
    American Society of Hematology
    Details
    Publication Date: 1987-12-01
    Description: Cytogenetic analysis of bone marrow cells and in vitro growth for bone marrow granulocytic-macrophage stem cells have been performed in 13 patients with mastocytosis, six with systemic mastocytosis, and seven with urticaria pigmentosa. Clones with chromosome abnormalities were found in five patients. The number of clusters and/or colonies after seven days in culture was increased in seven patients, compared with the growth in a control group. Three patients with chromosome abnormalities showed an abnormal growth pattern, yet exhibited normal peripheral blood values. Two patients with systemic mastocytosis had clones with chromosome abnormalities and some abnormal hematological values. The proportion of patients with chromosome abnormalities and an abnormal growth pattern was higher among these patients with mastocytosis than in healthy control subjects. These results may be of interest when discussing the origin of mast cell disorders and indicate an association with the myeloproliferative disorders.
    Print ISSN: 0006-4971
    Electronic ISSN: 1528-0020
    Topics: Biology , Medicine
    Published by American Society of Hematology
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  • 5
    Electronic Resource
    Electronic Resource
    Electrical transcutaneous nerve stimulation for relief of itch (1975)
    Springer
    Cellular and molecular life sciences 31 (1975), S. 191-191 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Résumé La stimulation électrique transcutanée a été employée pour des patients atteints de prurigo. Dans 17 cas de personnes traitées, 14 ont été délivrées de leur mal pendant des périodes qui varièrent de quelques heures à une semaine. La base neurophysiologique de cet effet n'est pas entièrement établie.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01990698
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    Paper (German National Licenses)
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