Publication Date:
2002-01-26
Description:
It is difficult to mix solutions in microchannels. Under typical operating conditions, flows in these channels are laminar-the spontaneous fluctuations of velocity that tend to homogenize fluids in turbulent flows are absent, and molecular diffusion across the channels is slow. We present a passive method for mixing streams of steady pressure-driven flows in microchannels at low Reynolds number. Using this method, the length of the channel required for mixing grows only logarithmically with the Peclet number, and hydrodynamic dispersion along the channel is reduced relative to that in a simple, smooth channel. This method uses bas-relief structures on the floor of the channel that are easily fabricated with commonly used methods of planar lithography.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stroock, Abraham D -- Dertinger, Stephan K W -- Ajdari, Armand -- Mezic, Igor -- Stone, Howard A -- Whitesides, George M -- GM51559/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2002 Jan 25;295(5555):647-51.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA. stroock@fas.harvard.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11809963" target="_blank"〉PubMed〈/a〉
Keywords:
Chemistry, Physical
;
Diffusion
;
Microchemistry
;
Miniaturization
;
Physicochemical Phenomena
;
Pressure
;
*Rheology/instrumentation
;
Viscosity
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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