ISSN:
1572-8781
Keywords:
microreactor
;
microfluidics
;
EPON SU-8
;
glucose
;
control pore glass
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
,
Technology
Notes:
Abstract This article describes the design, fabrication and initial testing of an enzymatic microreactor using Si, glass, epoxy and Perspex components. The microreactor geometry was defined by a photostructured EPON SU-8 spacer. This gave two chambers, an upstream chamber (vol. ∼2.7 μl) which was packed with control pore glass (CPG) and a downstream chamber (vol. ∼1.5 μl) which contained the detectors. Eleven EPON SU-8 columns separated the chambers and prevented the CPG from passing. Glucose detection via glucose oxidase immobilized to the CPG was used as a model system. Conversion efficiencies between 15 and 60% at flow rates of 150 and 26 μ1 min−1 respectively were obtained. Overall the system was found to be robust and to have a lifetime of at least one month.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1009972210811
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